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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Ritonavir | |
| Synonyms |
Norvir RIT RITONAVIR Ritonavir ritonavir |
|
| Definitions |
A peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cytochrome P450. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1609 |
|
| ALT_DEFINITION |
A drug used to treat infection with HIV (the virus that causes AIDS). It is also being studied in the treatment of some types of cancer. Ritonavir blocks the ability of HIV to make copies of itself and may block the growth of cancer cells. It is a type of anti-HIV agent and a type of protease inhibitor.
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| CAS_Registry |
155213-67-5
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|
| CHEBI_ID |
CHEBI:45409
|
|
| Chemical_Formula |
C37H48N6O5S2
|
|
| code |
C1609
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173381 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C173383 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
A peptidomimetic agent that inhibits both HIV-1 and HIV-2 proteases. Ritonavir is highly inhibited by serum proteins but boosts the effect of other HIV proteases by blocking their degradation by cytochrome P450.
|
|
| Display_Name |
Ritonavir
|
|
| FDA_UNII_Code |
O3J8G9O825
|
|
| FULL_SYN |
Norvir RIT RITONAVIR Ritonavir ritonavir
|
|
| label |
Ritonavir
|
|
| Legacy Concept Name |
Ritonavir
|
|
| NCI_Drug_Dictionary_ID |
42665
|
|
| NSC Number |
693184
|
|
| PDQ_Closed_Trial_Search_ID |
42665
|
|
| PDQ_Open_Trial_Search_ID |
42665
|
|
| Preferred_Name |
Ritonavir
|
|
| prefixIRI |
Thesaurus:C1609
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0292818
|
|
| subClassOf |
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