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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Bupropion Hydrochloride | |
| Synonyms |
Bupropion Hydrochloride Amfebutamone (+-)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone Hydrochloride BUPROPION HYDROCHLORIDE BW 323U66 Wellbutrin |
|
| Definitions |
The hydrochloride salt of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation and improving sexual desire. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine and is a central nicotinic acetylcholine receptor antagonist. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1317 |
|
| Accepted_Therapeutic_Use_For |
Depression; Smoking cessation
|
|
| CAS_Registry |
31677-93-7
|
|
| Chemical_Formula |
C13H18ClNO.HCl
|
|
| code |
C1317
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
The hydrochloride salt of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation and improving sexual desire. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine and is a central nicotinic acetylcholine receptor antagonist.
|
|
| Display_Name |
Bupropion Hydrochloride
|
|
| FDA_UNII_Code |
ZG7E5POY8O
|
|
| FULL_SYN |
Bupropion Hydrochloride Amfebutamone (+-)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone Hydrochloride BUPROPION HYDROCHLORIDE BW 323U66 Wellbutrin
|
|
| Has_Free_Acid_Or_Base_Form | ||
| label |
Bupropion Hydrochloride
|
|
| Legacy Concept Name |
Bupropion
|
|
| NCI_Drug_Dictionary_ID |
38567
|
|
| NSC Number |
315851
|
|
| PDQ_Closed_Trial_Search_ID |
38567
|
|
| PDQ_Open_Trial_Search_ID |
38567
|
|
| Preferred_Name |
Bupropion Hydrochloride
|
|
| prefixIRI |
Thesaurus:C1317
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0085934
|
|
| subClassOf |
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