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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Venlafaxine | |
| Synonyms |
venlafaxine Venlafaxine VENLAFAXINE |
|
| Definitions |
A synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04) |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1278 |
|
| Accepted_Therapeutic_Use_For |
Anxiety; Depression
|
|
| ALT_DEFINITION |
An antidepressant drug that is being evaluated for the treatment of hot flashes in women who have breast cancer.
|
|
| CAS_Registry |
93413-69-5
|
|
| CHEBI_ID |
CHEBI:9943
|
|
| Chemical_Formula |
C17H27NO2
|
|
| code |
C1278
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 |
|
| Contributing_Source |
CTRP FDA
|
|
| DEFINITION |
A synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04)
|
|
| Display_Name |
Venlafaxine
|
|
| FDA_UNII_Code |
GRZ5RCB1QG
|
|
| FULL_SYN |
venlafaxine Venlafaxine VENLAFAXINE
|
|
| Has_Salt_Form | ||
| label |
Venlafaxine
|
|
| Legacy Concept Name |
Venlafaxine
|
|
| NCI_Drug_Dictionary_ID |
43238
|
|
| PDQ_Closed_Trial_Search_ID |
43238
|
|
| PDQ_Open_Trial_Search_ID |
43238
|
|
| Preferred_Name |
Venlafaxine
|
|
| prefixIRI |
Thesaurus:C1278
|
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
|
|
| UMLS_CUI |
C0078569
|
|
| subClassOf |
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