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National Cancer Institute Thesaurus
Last uploaded:
February 23, 2024
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| Preferred Name | Antithrombin-III | |
| Synonyms |
Antithrombin-III Antithrombin III Serine-Cysteine Proteinase Inhibitor Clade C Member 1 ATIII SERPINC1 Serpin C1 |
|
| Definitions |
Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase activity during blood coagulation. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104683 |
|
| code |
C104683
|
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP
|
|
| DEFINITION |
Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase activity during blood coagulation.
|
|
| DesignNote |
Antithrombin-III can inhibit thrombin, matriptase-3/TMPRSS7, and coagulation factors IXa, Xa and Xia. (UniProt)
|
|
| Display_Name |
Antithrombin-III
|
|
| FULL_SYN |
Antithrombin-III Antithrombin III Serine-Cysteine Proteinase Inhibitor Clade C Member 1 ATIII SERPINC1 Serpin C1
|
|
| label |
Antithrombin-III
|
|
| NCI_META_CUI |
CL360008
|
|
| OMIM_Number |
107300
|
|
| Preferred_Name |
Antithrombin-III
|
|
| prefixIRI |
Thesaurus:C104683
|
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
|
|
| Swiss_Prot |
P01008
|
|
| subClassOf |
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