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Mondo Disease Ontology
| Preferred Name | patent foramen ovale | |
| Synonyms |
patent foramen ovale (disease) ostium secundum type atrial septal defect foramen ovale patent atrial septal defect within oval fossa patent foramen ovale persistent ostium secundum defect, patent or persistent, ostium secundum |
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| Definitions |
A persistent opening in the atrial septum after birth. While a normal part of fetal circulation, the foramen ovale should close once the newborn begins breathing and the pressure in the left atrium exceeds that of the right atrium. While a PFO is generally asymptomatic, it can lead to the passage of clots from the venous circulation into the artierial circulation, resulting in paradoxical emboli, and possible strokes. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0020439 |
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| database_cross_reference |
Orphanet:99108 NCIT:C34619 MESH:D054092 NANDO:2200266 DOID:13620 HP:0001655 UMLS:C0016522 MEDGEN:8891 MedDRA:10016982
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|
| definition |
A persistent opening in the atrial septum after birth. While a normal part of fetal circulation, the foramen ovale should close once the newborn begins breathing and the pressure in the left atrium exceeds that of the right atrium. While a PFO is generally asymptomatic, it can lead to the passage of clots from the venous circulation into the artierial circulation, resulting in paradoxical emboli, and possible strokes.
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| has_exact_synonym |
patent foramen ovale (disease) ostium secundum type atrial septal defect foramen ovale patent atrial septal defect within oval fossa patent foramen ovale persistent ostium secundum defect, patent or persistent, ostium secundum
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| IAO_0000589 |
patent foramen ovale (disease)
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| id |
MONDO:0020439
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-simple#rare http://purl.obolibrary.org/obo/mondo/mondo-simple#ordo_morphological_anomaly http://purl.obolibrary.org/obo/mondo/mondo-simple#inferred_rare |
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| label |
patent foramen ovale
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| notation |
MONDO:0020439
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| prefLabel |
patent foramen ovale
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| skos_closeMatch | ||
| skos_exactMatch |
http://purl.obolibrary.org/obo/NCIT_C34619 http://linkedlifedata.com/resource/umls/id/C0016522 http://purl.obolibrary.org/obo/DOID_13620 |
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