loading...| Preferred Name | anaplastic astrocytoma | |
| Synonyms |
grade III astrocytic tumor anaplastic astrocytoma grade III astrocytoma malignant astrocytoma astrocytoma, anaplastic, malignant grade III astrocytic tumour grade III astrocytic neoplasm |
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| Definitions |
Anaplastic astrocytoma is a rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0016684 |
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| database_cross_reference |
NANDO:2200086 Orphanet:251589 NORD:769 DOID:3078 GARD:5860 ICDO:9401/3 MEDGEN:137784 EFO:0002499 MedDRA:10002224 ONCOTREE:AASTR UMLS:C0334579 NCIT:C9477 MedDRA:10060971 |
|
| definition |
Anaplastic astrocytoma is a rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord. |
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| has_exact_synonym |
grade III astrocytic tumor anaplastic astrocytoma grade III astrocytoma malignant astrocytoma astrocytoma, anaplastic, malignant grade III astrocytic tumour grade III astrocytic neoplasm |
|
| id |
MONDO:0016684 |
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-simple#otar http://purl.obolibrary.org/obo/mondo/mondo-simple#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-simple#rare http://purl.obolibrary.org/obo/mondo/mondo-simple#ordo_disorder |
|
| label |
anaplastic astrocytoma |
|
| notation |
MONDO:0016684 |
|
| prefLabel |
anaplastic astrocytoma |
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| skos_closeMatch | ||
| skos_exactMatch |
http://linkedlifedata.com/resource/umls/id/C0334579 http://purl.obolibrary.org/obo/NCIT_C9477 http://identifiers.org/medgen/137784 http://purl.obolibrary.org/obo/EFO_0002499 |
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| treeView |
http://purl.obolibrary.org/obo/MONDO_0016680 |
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| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0016680 |