loading...| Preferred Name | acute monocytic leukemia | |
| Synonyms |
acute monoblastic/monocytic leukaemia leukemia, acute monocytic acute monoblastic leukaemia acute myeloblastic leukaemia type 5 AML-M5 acute myeloblastic leukemia type 5 acute monoblastic/monocytic leukemia acute monoblastic leukemia monocytic leukaemia monocytic leukemia acute monocytic leukaemia (FAB M5b) monocytic leukemia, acute acute monocytic leukemia, FAB M5 AML M5 acute monocytic leukemia, morphology acute monocytic leukaemia (FAB M5B) acute monocytic leukemia (FAB M5B) acute monocytic leukemia (FAB M5b) acute monocytic leukemia, morphology (morphologic abnormality) acute monoblastic leukaemia and acute monocytic leukaemia leukemia, monocytic, malignant acute monoblastic leukemia and acute monocytic leukemia acute monocytic leukaemia without mention of remission acute monocytic leukemia acute monocytic leukemia without mention of remission |
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| Definitions |
Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with asthenia, pallor, fever, and dizziness. Specific features of AML-M5 include hyperleukocytosis, propensity for extramedullary infiltrates, coagulation abnormalities including disseminated intravascular coagulation and neurological disorders. Leukemia cutis and gingival infiltration can also be seen. A characteristic translocation observed in AML-M5 is t(9;11). |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0007896 |
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| database_cross_reference |
EFO:0000221 OMIM:151380 ICDO:9891/3 icd11.foundation:517546180 GARD:525 UMLS:C0023465 NCIT:C4861 MEDGEN:7319 SCTID:413441006 CSP:2004-2820 MedDRA:10000871 Orphanet:514 MedDRA:10059439 NANDO:2200008 ONCOTREE:AMOL NANDO:2200009 DOID:8864 ICD9:206.0 MESH:D007948 |
|
| definition |
Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with asthenia, pallor, fever, and dizziness. Specific features of AML-M5 include hyperleukocytosis, propensity for extramedullary infiltrates, coagulation abnormalities including disseminated intravascular coagulation and neurological disorders. Leukemia cutis and gingival infiltration can also be seen. A characteristic translocation observed in AML-M5 is t(9;11). |
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| excluded_from_qc_check |
http://purl.obolibrary.org/obo/mondo/sparql/qc/mondo/qc-omim-subsumption.sparql |
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| has_broad_synonym |
monocytic leukaemia monocytic leukemia |
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| has_exact_synonym |
acute monocytic leukaemia (FAB M5b) monocytic leukemia, acute acute monocytic leukemia, FAB M5 AML M5 acute monocytic leukemia, morphology acute monocytic leukaemia (FAB M5B) acute monocytic leukemia (FAB M5B) acute monocytic leukemia (FAB M5b) acute monocytic leukemia, morphology (morphologic abnormality) acute monoblastic leukaemia and acute monocytic leukaemia leukemia, monocytic, malignant acute monoblastic leukemia and acute monocytic leukemia acute monocytic leukaemia without mention of remission acute monocytic leukemia acute monocytic leukemia without mention of remission |
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| has_related_synonym |
acute monoblastic/monocytic leukaemia leukemia, acute monocytic acute monoblastic leukaemia acute myeloblastic leukaemia type 5 AML-M5 acute myeloblastic leukemia type 5 acute monoblastic/monocytic leukemia acute monoblastic leukemia |
|
| id |
MONDO:0007896 |
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| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-simple#otar http://purl.obolibrary.org/obo/mondo/mondo-simple#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-simple#rare http://purl.obolibrary.org/obo/mondo/mondo-simple#ordo_disorder |
|
| label |
acute monocytic leukemia |
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| notation |
MONDO:0007896 |
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| prefLabel |
acute monocytic leukemia |
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| seeAlso |
https://rarediseases.info.nih.gov/diseases/525/acute-monoblastic-leukemia |
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| skos_closeMatch | ||
| skos_exactMatch |
http://identifiers.org/medgen/7319 http://purl.obolibrary.org/obo/Orphanet_514 http://purl.obolibrary.org/obo/EFO_0000221 http://linkedlifedata.com/resource/umls/id/C0023465 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/517546180 http://purl.obolibrary.org/obo/NCIT_C4861 http://identifiers.org/mesh/D007948 |
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| treeView | ||
| excluded subClassOf | ||
| subClassOf |