loading...| Preferred Name | kuru | |
| Synonyms |
kuru encephalopathy |
|
| Definitions |
A prion disease found exclusively among the Fore linguistic group natives of the highlands of new guinea. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) |
|
| ID |
http://purl.obolibrary.org/obo/MONDO_0006825 |
|
| closeMatch | ||
| database_cross_reference |
Orphanet:454745 MESH:D007729 ICD9:046.0 ICD10CM:A81.81 EFO:1001008 DOID:648 UMLS:C0022802 SCTID:86188000 icd11.foundation:553889510 GARD:7617 MedDRA:10023497 |
|
| definition |
A prion disease found exclusively among the Fore linguistic group natives of the highlands of new guinea. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773) |
|
| disease arises from feature | ||
| exactMatch |
http://purl.obolibrary.org/obo/Orphanet_454745 http://linkedlifedata.com/resource/umls/id/C0022802 http://identifiers.org/mesh/D007729 http://purl.bioontology.org/ontology/ICD10CM/A81.81 |
|
| has_exact_synonym |
kuru encephalopathy |
|
| id |
MONDO:0006825 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#nord_rare http://purl.obolibrary.org/obo/mondo#orphanet_rare |
|
| label |
kuru |
|
| notation |
MONDO:0006825 |
|
| prefLabel |
kuru |
|
| seeAlso | ||
| treeView |
http://purl.obolibrary.org/obo/MONDO_0005395 |
|
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0005395 |