loading...| Preferred Name | keratoacanthoma | |
| Synonyms | ||
| Definitions |
A dome-shaped, rapidly growing skin lesion composed of well differentiated squamous cells. It represents a proliferation of the infundibular epithelium of the hair follicle and its morphologic distinction from a well differentiated carcinoma may be difficult or impossible. Keratoacanthomas affect males more frequently than females and the majority tend to regress spontaneously. It has been suggested that keratoacanthoma represents a distinct subtype of squamous cell carcinoma of the skin. Clinically and histologically, it may be confused with a de novo highly malignant squamous cell carcinoma (SCC). However, KA may be viewed as an abortive cancer that only rarely progresses into an aggressive SCC - PMID:8277007. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0002527 |
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| comment |
Clinically and histologically, it may be confused with a de novo highly malignant squamous cell carcinoma (SCC). However, KA may be viewed as an abortive cancer that only rarely progresses into an aggressive SCC - PMID:8277007. |
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| database_cross_reference |
SCTID:254662007 MEDGEN:5954 NCIT:C3146 icd11.foundation:516478127 UMLS:C0022572 MESH:D007636 ICDO:8071/1 DOID:3149 |
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| definition |
A dome-shaped, rapidly growing skin lesion composed of well differentiated squamous cells. It represents a proliferation of the infundibular epithelium of the hair follicle and its morphologic distinction from a well differentiated carcinoma may be difficult or impossible. Keratoacanthomas affect males more frequently than females and the majority tend to regress spontaneously. It has been suggested that keratoacanthoma represents a distinct subtype of squamous cell carcinoma of the skin. |
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| id |
MONDO:0002527 |
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| in_subset | ||
| label |
keratoacanthoma |
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| notation |
MONDO:0002527 |
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| prefLabel |
keratoacanthoma |
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| skos_exactMatch |
http://identifiers.org/mesh/D007636 http://purl.obolibrary.org/obo/NCIT_C3146 http://linkedlifedata.com/resource/umls/id/C0022572 http://identifiers.org/snomedct/254662007 http://purl.obolibrary.org/obo/DOID_3149 http://identifiers.org/medgen/5954 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/516478127 |
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