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Myocardial Infarction Ontology
Last uploaded:
December 18, 2024
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| Preferred Name | metoprolol | |
| Synonyms |
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| Definitions |
A cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction leading to a reduction in cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion. [url:http://purl.obolibrary.org/obo/NCIT_C61845] |
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| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02871 |
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| definition |
A cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction leading to a reduction in cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thereby preventing vasoconstriction and aldosterone secretion. [url:http://purl.obolibrary.org/obo/NCIT_C61845]
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| label |
metoprolol
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| MIO_ID |
MIO:02871
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| prefLabel |
metoprolol
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| reference |
UMLS:C0025859 NCIT:C61845 CHEBI:6904
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| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02649 |
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