loading...| Preferred Name | statin | |
| Synonyms |
HMG-CoA reductase inhibitors hydroxymethylglutaryl coenzymeA reductase inhibitors hydroxymethylglutaryl-coenzyme A reductase inhibitor hydroxymethylglutaryl coenzymeA reductase inhibitor HMG-CoA reductase inhibitor statins |
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| Definitions |
Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs. [url:https://en.wikipedia.org/wiki/Statin] The available evidence indicates clear and conclusive benefits of statins in the primary prevention of MI and stroke. In numerous randomized trials of over 170 000 patients in primary and secondary prevention, as well as their meta-analyses, statins produce both statistically and clinically significant reductions in MI and stroke as well as CVD and total mortality.[url:https://pubmed.ncbi.nlm.nih.gov/30563358/] |
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| ID |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01067 |
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| comment |
The available evidence indicates clear and conclusive benefits of statins in the primary prevention of MI and stroke. In numerous randomized trials of over 170 000 patients in primary and secondary prevention, as well as their meta-analyses, statins produce both statistically and clinically significant reductions in MI and stroke as well as CVD and total mortality.[url:https://pubmed.ncbi.nlm.nih.gov/30563358/] |
|
| definition |
Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs. [url:https://en.wikipedia.org/wiki/Statin] |
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| label |
statin |
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| MIO_ID |
MIO:01067 |
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| prefLabel |
statin |
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| reference |
CHEBI:87631 |
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| synonyms |
HMG-CoA reductase inhibitors hydroxymethylglutaryl coenzymeA reductase inhibitors hydroxymethylglutaryl-coenzyme A reductase inhibitor hydroxymethylglutaryl coenzymeA reductase inhibitor HMG-CoA reductase inhibitor statins |
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| subClassOf |
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00543 http://www.semanticweb.org/admin/ontologies/2022/7/MIO:00523 |