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Medical Subject Headings
| Preferred Name | Spironolactone | |
| Synonyms |
Aquareduct SC-9420 Spirobeta Spironone SC 9420 Spirolactone Novo-Spiroton Verospiron Flumach Spiro Von Ct Verospirone Espironolactona Mundogen Veroshpiron Spiro L.U.T. Spirospare Espironolactona Alter Von Ct, Spiro Ct, Spiro Von Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)- Spiractin Practon Spirolang Spirono-Isis Frumikal Novo Spiroton NovoSpiroton Spirogamma Aldactone A Jenaspiron Spirono Isis Duraspiron SC9420 Aldactone |
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| Definitions |
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827) |
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| ID |
http://purl.bioontology.org/ontology/MESH/D013148 |
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| altLabel |
Aquareduct SC-9420 Spirobeta Spironone SC 9420 Spirolactone Novo-Spiroton Verospiron Flumach Spiro Von Ct Verospirone Espironolactona Mundogen Veroshpiron Spiro L.U.T. Spirospare Espironolactona Alter Von Ct, Spiro Ct, Spiro Von Pregn-4-ene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, gamma-lactone, (7alpha,17alpha)- Spiractin Practon Spirolang Spirono-Isis Frumikal Novo Spiroton NovoSpiroton Spirogamma Aldactone A Jenaspiron Spirono Isis Duraspiron SC9420 Aldactone
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| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
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|
| cui |
C0592135 C0600340 C1564174 C1564159 C0701471 C0591054 C1564157 C1564173 C1564166 C1564162 C1564160 C1564194 C1564193 C1564163 C1564156 C1564155 C1564154 C0037982 C1564161 C1564165 C1564158 C0701468 C1564164
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|
| DC |
1
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|
| definition |
A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
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|
| DX |
19660101
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| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
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| Inverse of RB |
27O7W4T232 0
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| isa | ||
| LT |
TRD
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| Mapped from |
http://purl.bioontology.org/ontology/MESH/C572034 http://purl.bioontology.org/ontology/MESH/C572033 http://purl.bioontology.org/ontology/MESH/C033554 http://purl.bioontology.org/ontology/MESH/C045343 http://purl.bioontology.org/ontology/MESH/C055913 http://purl.bioontology.org/ontology/MESH/C048998 http://purl.bioontology.org/ontology/MESH/C019225 http://purl.bioontology.org/ontology/MESH/C045746 http://purl.bioontology.org/ontology/MESH/C026063 http://purl.bioontology.org/ontology/MESH/C016699 http://purl.bioontology.org/ontology/MESH/C032299 http://purl.bioontology.org/ontology/MESH/C070473 http://purl.bioontology.org/ontology/MESH/C054537 http://purl.bioontology.org/ontology/MESH/C051308 http://purl.bioontology.org/ontology/MESH/C058465 http://purl.bioontology.org/ontology/MESH/C016210 http://purl.bioontology.org/ontology/MESH/C107482 http://purl.bioontology.org/ontology/MESH/C550428 http://purl.bioontology.org/ontology/MESH/C115980 http://purl.bioontology.org/ontology/MESH/C115981 http://purl.bioontology.org/ontology/MESH/C058243 http://purl.bioontology.org/ontology/MESH/C047175 http://purl.bioontology.org/ontology/MESH/C424563 http://purl.bioontology.org/ontology/MESH/C061691 http://purl.bioontology.org/ontology/MESH/C014143 http://purl.bioontology.org/ontology/MESH/C010768 http://purl.bioontology.org/ontology/MESH/C041006 http://purl.bioontology.org/ontology/MESH/C006286 http://purl.bioontology.org/ontology/MESH/C072356 http://purl.bioontology.org/ontology/MESH/C058412 |
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| MDA |
19990101
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|
| MMR |
20170524
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|
| MN |
D04.210.500.745.745.855 D02.540.679
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|
| notation |
D013148
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|
| PA |
D004232 D000451
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|
| prefLabel |
Spironolactone
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|
| RR |
52-01-7 (Spironolactone)
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|
| TERMUI |
T000912891 T618540 T618544 T618536 T618532 T618534 T618592 T618590 T038655 T618542 T618538 T618733 T618524 T000912890 T038656 T038653 T038654 T618528 T038658 T038659 T038652 T038657 T618594 T618548 T618731 T618530
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|
| TH |
NLM (1996) US UK CA NLM (1990) FDA SRS (2014) ES UNK (19XX) INN (19XX) DE AU USP (19XX) BAN (19XX) FR
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|
| tui |
T109 T121
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| subClassOf |
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