loading...| Preferred Name |
Puberty, Precocious |
|
| Synonyms |
Male-Limited Precocious Puberties |
|
| Definitions |
Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D011629 |
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| altLabel |
Male-Limited Precocious Puberties Puberties, Precocious Praecox, Pubertas Precocious Puberty, Male Limited Precocious Puberties, Familial Puberty, Central Precocious Precocities, Sexual Puberty, Male-Limited Precocious Puberties, Familial Precocious Central Precocious Puberties Central Precocious Puberty Precocities, Idiopathic Sexual Precocious Puberty, Central Puberty, Familial Precocious Sexual Precocity, Idiopathic Sexual Precocity Precocity, Sexual Idiopathic Sexual Precocity Precocious Puberty, Male-Limited Puberties, Central Precocious Familial Precocious Puberties Puberties, Male-Limited Precocious Testotoxicosis Male-Limited Precocious Puberty Idiopathic Sexual Precocities Sexual Precocities Precocious Puberties, Central Precocious Puberty, Familial Sexual Precocities, Idiopathic Precocious Puberties Precocious Puberties, Male-Limited Familial Precocious Puberty Pubertas Praecox Precocity, Idiopathic Sexual Precocious Puberty |
|
| AN |
human only |
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| AQL |
BL CF CI CL CO DG DH DI DT EC EH EM EN EP ET GE HI IM ME MI MO NU PA PC PP PS PX RH RT SU TH UR VI |
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| cui |
C0034013 C0342543 C0271527 C1504412 |
|
| DC |
1 |
|
| definition |
Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE. An autosomal dominant hereditary disorder that is characterized by gonadotropin-dependent precocious puberty due to early activation of the hypothalamic-pituitary-gonadal axis. A mutation in the KISS1R gene has been identified. OMIM: 176400 Familial precocious puberty in boys usually presents by age 4 with rapid VIRILIZATION and is also characterized by gonadotropin-independent testosterone secretion, low secretion of LUTEINIZING HORMONE, and advanced SPERMATOGENESIS in the testis. Mutations in the LHCGR gene have been identified. OMIM: 176410 |
|
| DX |
19660101 |
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| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000178 http://purl.bioontology.org/ontology/MESH/Q000175 http://purl.bioontology.org/ontology/MESH/Q000628 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000139 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000517 http://purl.bioontology.org/ontology/MESH/Q000469 http://purl.bioontology.org/ontology/MESH/Q000150 http://purl.bioontology.org/ontology/MESH/Q000821 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000196 http://purl.bioontology.org/ontology/MESH/Q000473 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000382 http://purl.bioontology.org/ontology/MESH/Q000451 http://purl.bioontology.org/ontology/MESH/Q000453 http://purl.bioontology.org/ontology/MESH/Q000534 http://purl.bioontology.org/ontology/MESH/Q000532 http://purl.bioontology.org/ontology/MESH/Q000503 http://purl.bioontology.org/ontology/MESH/Q000188 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000201 http://purl.bioontology.org/ontology/MESH/Q000209 http://purl.bioontology.org/ontology/MESH/Q000208 http://purl.bioontology.org/ontology/MESH/Q000601 http://purl.bioontology.org/ontology/MESH/Q000000981 http://purl.bioontology.org/ontology/MESH/Q000652 |
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| Inverse of RO | ||
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C536961 http://purl.bioontology.org/ontology/MESH/C000726751 http://purl.bioontology.org/ontology/MESH/C567566 http://purl.bioontology.org/ontology/MESH/C564568 http://purl.bioontology.org/ontology/MESH/C567168 |
|
| MDA |
19990101 |
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| MMR |
20180228 |
|
| MN |
C19.391.693 |
|
| notation |
D011629 |
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| prefLabel |
Puberty, Precocious |
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| TERMUI |
T741004 T000935870 T801503 T000935872 T741007 T034340 T801502 T000935873 T609186 T000935871 |
|
| TH |
OMIM (2013) NLM (1966) OMIM (2014) GHR (2014) NLM (2006) ORD (2010) |
|
| tui |
T047 |
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| subClassOf |