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Last uploaded: January 31, 2024

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Preferred Name	Naltrexone
Synonyms	EN-1639A
Definitions	Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
ID	http://purl.bioontology.org/ontology/MESH/D009271
altLabel	EN-1639A Nalorex Naltrexone Hydrochloride Trexan EN1639A ReVia EN 1639A Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)- Celupan Nemexin Antaxone
AQL	AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
cui	C0355800 C1449896 C0027360 C1449897 C5234921 C0591842 C0729157 C5234920 C0014022
DC	1
definition	Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
DX	19860101
HN	1986 (1976)
Inverse of AQ	http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 http://purl.bioontology.org/ontology/MESH/Q000652 http://purl.bioontology.org/ontology/MESH/Q000528
Inverse of RB	Z6375YW9SF 0 5S6W795CQM
isa	http://purl.bioontology.org/ontology/MESH/D000427 http://purl.bioontology.org/ontology/MESH/D009292
LT	TRD
Machine permutation	1986; NALTREXONE was indexed under NALOXONE 1976-1985
Mapped from	http://purl.bioontology.org/ontology/MESH/C000621664 http://purl.bioontology.org/ontology/MESH/C546970 http://purl.bioontology.org/ontology/MESH/C017120 http://purl.bioontology.org/ontology/MESH/C043916 http://purl.bioontology.org/ontology/MESH/C078619 http://purl.bioontology.org/ontology/MESH/C078618 http://purl.bioontology.org/ontology/MESH/C500352 http://purl.bioontology.org/ontology/MESH/C000624616 http://purl.bioontology.org/ontology/MESH/C550436 http://purl.bioontology.org/ontology/MESH/C571180 http://purl.bioontology.org/ontology/MESH/C469345 http://purl.bioontology.org/ontology/MESH/C469346 http://purl.bioontology.org/ontology/MESH/C000624286 http://purl.bioontology.org/ontology/MESH/C053394 http://purl.bioontology.org/ontology/MESH/C053393 http://purl.bioontology.org/ontology/MESH/C500055 http://purl.bioontology.org/ontology/MESH/C024524 http://purl.bioontology.org/ontology/MESH/C054867 http://purl.bioontology.org/ontology/MESH/C040902 http://purl.bioontology.org/ontology/MESH/C568302 http://purl.bioontology.org/ontology/MESH/C032257 http://purl.bioontology.org/ontology/MESH/C051843 http://purl.bioontology.org/ontology/MESH/C051844 http://purl.bioontology.org/ontology/MESH/C000608978 http://purl.bioontology.org/ontology/MESH/C114628 http://purl.bioontology.org/ontology/MESH/C050735 http://purl.bioontology.org/ontology/MESH/C000606131 http://purl.bioontology.org/ontology/MESH/C046003 http://purl.bioontology.org/ontology/MESH/C049799 http://purl.bioontology.org/ontology/MESH/C107547 http://purl.bioontology.org/ontology/MESH/C000620491 http://purl.bioontology.org/ontology/MESH/C073580 http://purl.bioontology.org/ontology/MESH/C079585 http://purl.bioontology.org/ontology/MESH/C079586 http://purl.bioontology.org/ontology/MESH/C119084 http://purl.bioontology.org/ontology/MESH/C502495 http://purl.bioontology.org/ontology/MESH/C502494 http://purl.bioontology.org/ontology/MESH/C503316 http://purl.bioontology.org/ontology/MESH/C055382 http://purl.bioontology.org/ontology/MESH/C066758 http://purl.bioontology.org/ontology/MESH/C086225 http://purl.bioontology.org/ontology/MESH/C545561 http://purl.bioontology.org/ontology/MESH/C028710 http://purl.bioontology.org/ontology/MESH/C499148 http://purl.bioontology.org/ontology/MESH/C077358 http://purl.bioontology.org/ontology/MESH/C000591595 http://purl.bioontology.org/ontology/MESH/C068868 http://purl.bioontology.org/ontology/MESH/C034641 http://purl.bioontology.org/ontology/MESH/C059502 http://purl.bioontology.org/ontology/MESH/C059503 http://purl.bioontology.org/ontology/MESH/C000626328 http://purl.bioontology.org/ontology/MESH/C044564 http://purl.bioontology.org/ontology/MESH/C115076 http://purl.bioontology.org/ontology/MESH/C115075 http://purl.bioontology.org/ontology/MESH/C086208 http://purl.bioontology.org/ontology/MESH/C025486 http://purl.bioontology.org/ontology/MESH/C424722 http://purl.bioontology.org/ontology/MESH/C043394 http://purl.bioontology.org/ontology/MESH/C487409 http://purl.bioontology.org/ontology/MESH/C038981 http://purl.bioontology.org/ontology/MESH/C000618349 http://purl.bioontology.org/ontology/MESH/C059551 http://purl.bioontology.org/ontology/MESH/C000717869 http://purl.bioontology.org/ontology/MESH/C532661 http://purl.bioontology.org/ontology/MESH/C532662 http://purl.bioontology.org/ontology/MESH/C576919 http://purl.bioontology.org/ontology/MESH/C010410 http://purl.bioontology.org/ontology/MESH/C493273 http://purl.bioontology.org/ontology/MESH/C000594989 http://purl.bioontology.org/ontology/MESH/C116266 http://purl.bioontology.org/ontology/MESH/C093324 http://purl.bioontology.org/ontology/MESH/C570718 http://purl.bioontology.org/ontology/MESH/C000619250 http://purl.bioontology.org/ontology/MESH/C503788 http://purl.bioontology.org/ontology/MESH/C437947 http://purl.bioontology.org/ontology/MESH/C035438 http://purl.bioontology.org/ontology/MESH/C562364 http://purl.bioontology.org/ontology/MESH/C034637 http://purl.bioontology.org/ontology/MESH/C068472 http://purl.bioontology.org/ontology/MESH/C064283 http://purl.bioontology.org/ontology/MESH/C580618 http://purl.bioontology.org/ontology/MESH/C106278
MDA	19750723
MMR	20180410
MN	D03.132.577.249.706.550 D03.605.497.750.550 D03.633.400.686.750.550 D04.615.723.795.706.550
notation	D009271
PA	D009292 D000427
prefLabel	Naltrexone
RR	Z6375YW9SF 16590-41-3 (Naltrexone)
TERMUI	T027672 T578691 T027673 T578693 T027674 T578690 T578695 T578699 T578700
TH	US UK NL NLM (2005) CA FDA SRS (2014) ES UNK (19XX) USAN (1963) INN (19XX) DE AU USP (19XX) BAN (19XX) FR IE
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/MESH/D009270

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/NDDF/001615	NDDF	CUI
http://purl.bioontology.org/ontology/ATC/N07BB04	ATC	CUI
http://purl.bioontology.org/ontology/RXNORM/152092	RXNORM	CUI
http://purl.bioontology.org/ontology/RCD/x02kK	RCD	CUI
http://purl.bioontology.org/ontology/MSHFRE/D009271	MSHFRE	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000179498	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/64191009	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000146867	NDFRT	CUI
http://purl.bioontology.org/ontology/VANDF/4018545	VANDF	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000040818	PDQ	CUI
http://purl.bioontology.org/ontology/RXNORM/105069	RXNORM	CUI
http://purl.bioontology.org/ontology/MSHFRE/D009271	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNMI/C-60D21	SNMI	CUI
http://purl.bioontology.org/ontology/SCTSPA/64191009	SCTSPA	CUI
http://purl.bioontology.org/ontology/RCD/x01GR	RCD	CUI
http://purl.bioontology.org/ontology/SCTSPA/373546002	SCTSPA	CUI
http://purl.bioontology.org/ontology/NDDF/004662	NDDF	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000147939	NDFRT	CUI
http://purl.bioontology.org/ontology/VANDF/4019853	VANDF	CUI
http://purl.bioontology.org/ontology/SCTSPA/87617007	SCTSPA	CUI
http://purl.bioontology.org/ontology/CSP/0092-7374	CRISP	CUI
http://purl.bioontology.org/ontology/LNC/LP15000-0	LOINC	CUI
http://purl.bioontology.org/ontology/RXNORM/7243	RXNORM	CUI
http://purl.bioontology.org/ontology/LNC/MTHU002303	LOINC	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/373546002	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/NDFRT/N0000007313	NDFRT	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/87617007	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/MSHFRE/D009271	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNMI/C-60D20	SNMI	CUI
http://purl.bioontology.org/ontology/PDQ/CDR0000040818	PDQ	CUI
http://purl.obolibrary.org/obo/CHEBI_7465	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_7465	CHEBI	LOOM
http://www.drugbank.ca/drugs/DB00704	FTC	LOOM
http://stirdf.jst.go.jp/id/200907019731414788	IOBC	LOOM
http://purl.jp/bio/4/id/200906073911164420	IOBC	LOOM
https://go.drugbank.com/drugs/DB00704	MDM	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8473	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.723.795.706.550	RH-MESH	LOOM
http://purl.obolibrary.org/obo/OMIT_0010305	OMIT	LOOM
http://purl.bioontology.org/ontology/ATC/N07BB04	ATC	LOOM
http://purl.bioontology.org/ontology/RCD/x01GR	RCD	LOOM
http://purl.obolibrary.org/obo/NCIT_C62055	BERO	LOOM
http://www.co-ode.org/ontologies/galen#Naltrexone	GALEN	LOOM
http://purl.obolibrary.org/obo/CHEBI_7465	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7465	DINTO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7465	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_7465	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_7465	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_7465	NIFSTD	LOOM
http://purl.bioontology.org/ontology/NDDF/004662	NDDF	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147939	NDFRT	LOOM
http://purl.bioontology.org/ontology/VANDF/4019853	VANDF	LOOM
http://purl.bioontology.org/ontology/CSP/0092-7374	CRISP	LOOM
http://purl.bioontology.org/ontology/LNC/LP15000-0	LOINC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62055	NCIT	LOOM
http://purl.bioontology.org/ontology/RXNORM/7243	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.577.249.706.550	RH-MESH	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.549.686.750.550	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU002303	LOINC	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373546002	SNOMEDCT	LOOM
http://purl.obolibrary.org/obo/MESH_D009271	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.497.750.550	RH-MESH	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass9a587443_7cc8_4915_a6bb_b7813fba79b7	WWECA	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018045	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0027360	OCHV	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Naltrexone	APAONTO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D009271	RH-MESH	LOOM
http://purl.bioontology.org/ontology/SNMI/C-60D20	SNMI	LOOM