loading...| Preferred Name |
beta 2-Microglobulin |
|
| Synonyms |
beta 2 Microglobulin |
|
| Definitions |
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D001613 |
|
| altLabel |
beta 2 Microglobulin Thymotaxin |
|
| AQL |
AD AE AG AI AN BI BL CF CH CL CS DE DF EC GE HI IM IP ME PD PH PK PO RE SD ST TO TU UL UR |
|
| cui |
C0005149 |
|
| DC |
1 |
|
| definition |
An 11-kDa protein associated with the outer membrane of many cells including LYMPHOCYTES. It is the small subunit of MHC CLASS I MOLECULES. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, CEREBROSPINAL FLUID, and urine of healthy individuals, and to a much greater degree in the urine and plasma of patients with tubular PROTEINURIA, renal failure, or kidney transplants. |
|
| DX |
19840101 |
|
| HN |
1991 (1975); use BETA 2 MICROGLOBULIN 1984-1990 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000172 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
0 |
|
| Machine permutation |
1991; see BETA 2 MICROGLOBULIN 1984-1990; BETA 2-MICROGLOBULIN was indexed under BETA GLOBULINS 1975-1983 |
|
| Mapped from | ||
| MDA |
19741119 |
|
| MMR |
20230316 |
|
| MN |
D23.050.705.552.100.175 D12.776.377.715.182.100 D12.776.543.550.439.100 D12.776.395.550.489.100 D09.400.430.890.489.100 D12.776.124.790.223.100 D23.050.301.500.100.175 |
|
| notation |
D001613 |
|
| prefLabel |
beta 2-Microglobulin |
|
| TERMUI |
T004640 T004641 |
|
| TH |
NLM (1991) NLM (1975) |
|
| tui |
T116 T123 |
|
| subClassOf |