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Last uploaded:
January 16, 2025
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| Id | http://purl.bioontology.org/ontology/MESH/D015395
http://purl.bioontology.org/ontology/MESH/D015395
|
|---|---|
| Preferred Name | Histocompatibility Antigens Class I |
| Definitions |
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
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| Synonyms |
MHC I Molecules
MHC I Peptide
Peptides, MHC-I
Class I Human Antigens
Class I Histocompatibility Antigen
Antigens, Class I
Class I Major Histocompatibility Molecules
Class I Antigens
Class I Histocompatibility Antigens
Class I MHC Protein
Human Class I Antigens
MHC-I Peptide
MHC Class I Molecules
Antigen, Class I
I Antigen, Class
Class I Major Histocompatibility Antigens
MHC-I Peptides
MHC I Peptides
MHC-I Molecules
MHC Class I Molecule
Class I Major Histocompatibility Antigen
Class I MHC Proteins
Peptide, MHC-I
Molecules, MHC-I
Class I Antigen
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells. |
|---|---|
| altLabel |
MHC I Molecules
MHC I Peptide
Peptides, MHC-I
Class I Human Antigens
Class I Histocompatibility Antigen
Antigens, Class I
Class I Major Histocompatibility Molecules
Class I Antigens
Class I Histocompatibility Antigens
Class I MHC Protein
Human Class I Antigens
MHC-I Peptide
MHC Class I Molecules
Antigen, Class I
I Antigen, Class
Class I Major Histocompatibility Antigens
MHC-I Peptides
MHC I Peptides
MHC-I Molecules
MHC Class I Molecule
Class I Major Histocompatibility Antigen
Class I MHC Proteins
Peptide, MHC-I
Molecules, MHC-I
Class I Antigen
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| prefLabel |
Histocompatibility Antigens Class I
|
| TH |
NLM (2019)
UNK (19XX)
NLM (2021)
NLM (1988)
|
| notation |
D015395
|
| DX |
19880101
|
| Machine permutation |
89
|
| MN |
D12.776.395.550.489
D23.050.705.552.100
D12.776.543.550.439
D09.400.430.890.489
D23.050.301.500.100
|
| FX |
D005805
|
| MMR |
20230316
|
| Mapped from |
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|
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PO RE TO TU UL UR
|
| HN |
89
|
| subClassOf | |
| Semantic type UMLS property | |
| Inverse of RB |
0
|
| DC |
1
|
| MDA |
19880606
|
| Inverse of RO | |
| type | |
| tui |
T109
T116
T129
|
| cui |
C0008897
C0019629
|
| AN |
human & animal
|
| Inverse of AQ |
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| TERMUI |
T045400
T045404
T001010128
T001010130
T001010129
T000936556
T001010127
T045402
T001010126
T000936553
T045403
T045401
T001010131
T000936554
T000936552
T045399
T000936555
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