loading...| Preferred Name |
Histocompatibility Antigens Class I |
|
| Synonyms |
MHC I Molecules MHC I Peptide Peptides, MHC-I Class I Human Antigens Class I Histocompatibility Antigen Antigens, Class I Class I Major Histocompatibility Molecules Class I Antigens Class I Histocompatibility Antigens Class I MHC Protein Human Class I Antigens MHC-I Peptide MHC Class I Molecules Antigen, Class I I Antigen, Class Class I Major Histocompatibility Antigens MHC-I Peptides MHC I Peptides MHC-I Molecules MHC Class I Molecule Class I Major Histocompatibility Antigen Class I MHC Proteins Peptide, MHC-I Molecules, MHC-I Class I Antigen |
|
| Definitions |
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D015395 |
|
| altLabel |
MHC I Molecules MHC I Peptide Peptides, MHC-I Class I Human Antigens Class I Histocompatibility Antigen Antigens, Class I Class I Major Histocompatibility Molecules Class I Antigens Class I Histocompatibility Antigens Class I MHC Protein Human Class I Antigens MHC-I Peptide MHC Class I Molecules Antigen, Class I I Antigen, Class Class I Major Histocompatibility Antigens MHC-I Peptides MHC I Peptides MHC-I Molecules MHC Class I Molecule Class I Major Histocompatibility Antigen Class I MHC Proteins Peptide, MHC-I Molecules, MHC-I Class I Antigen |
|
| AN |
human & animal |
|
| AQL |
AD AE AN BI BL CF CH CL DE EC GE HI IM IP ME PD PH PO RE TO TU UL UR |
|
| cui |
C0008897 C0019629 |
|
| DC |
1 |
|
| definition |
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells. |
|
| DX |
19880101 |
|
| FX |
D005805 |
|
| HN |
89 |
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000096 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000648 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000502 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000187 http://purl.bioontology.org/ontology/MESH/Q000235 http://purl.bioontology.org/ontology/MESH/Q000633 |
|
| Inverse of RB |
0 |
|
| Inverse of RO | ||
| Machine permutation |
89 |
|
| Mapped from |
http://purl.bioontology.org/ontology/MESH/C089390 http://purl.bioontology.org/ontology/MESH/C089395 http://purl.bioontology.org/ontology/MESH/C099187 http://purl.bioontology.org/ontology/MESH/C062341 http://purl.bioontology.org/ontology/MESH/C025625 http://purl.bioontology.org/ontology/MESH/C438668 http://purl.bioontology.org/ontology/MESH/C070296 http://purl.bioontology.org/ontology/MESH/C104779 http://purl.bioontology.org/ontology/MESH/C483818 http://purl.bioontology.org/ontology/MESH/C098080 http://purl.bioontology.org/ontology/MESH/C112461 http://purl.bioontology.org/ontology/MESH/C059600 http://purl.bioontology.org/ontology/MESH/C066649 http://purl.bioontology.org/ontology/MESH/C050453 http://purl.bioontology.org/ontology/MESH/C100688 http://purl.bioontology.org/ontology/MESH/C083041 http://purl.bioontology.org/ontology/MESH/C094840 http://purl.bioontology.org/ontology/MESH/C508874 http://purl.bioontology.org/ontology/MESH/C063775 http://purl.bioontology.org/ontology/MESH/C468260 http://purl.bioontology.org/ontology/MESH/C000708707 http://purl.bioontology.org/ontology/MESH/C040588 http://purl.bioontology.org/ontology/MESH/C110764 http://purl.bioontology.org/ontology/MESH/C051220 http://purl.bioontology.org/ontology/MESH/C490628 http://purl.bioontology.org/ontology/MESH/C490627 http://purl.bioontology.org/ontology/MESH/C032907 http://purl.bioontology.org/ontology/MESH/C039692 http://purl.bioontology.org/ontology/MESH/C102231 http://purl.bioontology.org/ontology/MESH/C063959 http://purl.bioontology.org/ontology/MESH/C078177 http://purl.bioontology.org/ontology/MESH/C092249 http://purl.bioontology.org/ontology/MESH/C488760 http://purl.bioontology.org/ontology/MESH/C448919 http://purl.bioontology.org/ontology/MESH/C085433 http://purl.bioontology.org/ontology/MESH/C063371 http://purl.bioontology.org/ontology/MESH/C063372 |
|
| MDA |
19880606 |
|
| MMR |
20230316 |
|
| MN |
D12.776.395.550.489 D23.050.705.552.100 D12.776.543.550.439 D09.400.430.890.489 D23.050.301.500.100 |
|
| notation |
D015395 |
|
| prefLabel |
Histocompatibility Antigens Class I |
|
| TERMUI |
T045400 T045404 T001010128 T001010130 T001010129 T000936556 T001010127 T045402 T001010126 T000936553 T045403 T045401 T001010131 T000936554 T000936552 T045399 T000936555 |
|
| TH |
NLM (2019) UNK (19XX) NLM (2021) NLM (1988) |
|
| tui |
T109 T116 T129 |
|
| subClassOf |