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Medical Subject Headings
| Preferred Name | Cilastatin, Imipenem Drug Combination | |
| Synonyms |
Imipenem - Cilastatin Sodium Imipenem-Cilastatin, Sodium Salt Primaxin Imipenem-Cilastatin Sodium Tienam 500 Imipenem Cilastatin, Sodium Salt Thienam Imipenem Cilastatin Sodium MK 0787 MK 0791 mixture Imipenem Cilastatin Imipenem - Cilastatin Zienam MK 0787-MK 0791 mixture MK 787 MK 791 mixture MK 787-MK 791 mixture Imipenem-Cilastatin Cilastatin, Imipenem |
|
| Definitions |
Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000077728 |
|
| altLabel |
Imipenem - Cilastatin Sodium Imipenem-Cilastatin, Sodium Salt Primaxin Imipenem-Cilastatin Sodium Tienam 500 Imipenem Cilastatin, Sodium Salt Thienam Imipenem Cilastatin Sodium MK 0787 MK 0791 mixture Imipenem Cilastatin Imipenem - Cilastatin Zienam MK 0787-MK 0791 mixture MK 787 MK 791 mixture MK 787-MK 791 mixture Imipenem-Cilastatin Cilastatin, Imipenem
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|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
|
| cui |
C0733695 C0733698 C0145923 C0733701 C0145617 C0071972 C0733696
|
|
| DC |
1
|
|
| definition |
Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.
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|
| DX |
20190101
|
|
| HN |
2019 (1985)
|
|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
85960-17-4 92309-29-0 0
|
|
| isa | ||
| LT |
TRD
|
|
| Machine permutation |
2019; CILASTATIN, IMIPENEM DRUG COMBINATION was indexed under CILASTATIN and IMIPENEM 1995-2018 and 1988-1994; under DRUG COMBINATIONS 1995-2018 and 1985-1994; and under CYCLOPROPANES and THIENAMYCINS 1985-1988
|
|
| MDA |
20180709
|
|
| MMR |
20180410
|
|
| MN |
D26.310.356 D10.251.355.325.200.500 D02.455.426.392.368.533.200.500 D02.065.589.099.124.300.500.500 D03.633.100.300.124.300.500.500
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|
| notation |
D000077728
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|
| PA |
D011480 D000900
|
|
| prefLabel |
Cilastatin, Imipenem Drug Combination
|
|
| RR |
85960-17-4 (Na salt)
|
|
| TERMUI |
T000941292 T000940941 T160285 T000940943 T000941293 T160281 T000940940 T160282 T160286 T160284 T000940942 T000940944 T000940945 T160283
|
|
| TH |
US NLM (2009) UK CA NLM (2019) NLM (1985) NLM (2010) AU
|
|
| tui |
T109 T195 T121
|
|
| subClassOf |
http://purl.bioontology.org/ontology/MESH/D015378 |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |