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Medical Subject Headings
Preferred Name | Imipenem | |
Synonyms |
MK-0787 Imipenem, Anhydrous MK 0787 Anhydrous Imipenem N-Formimidoylthienamycin Imipenem Anhydrous N Formimidoylthienamycin 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))- Imipemide Anhydrous, Imipenem MK0787 |
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Definitions |
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor. |
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ID |
http://purl.bioontology.org/ontology/MESH/D015378 |
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altLabel |
MK-0787 Imipenem, Anhydrous MK 0787 Anhydrous Imipenem N-Formimidoylthienamycin Imipenem Anhydrous N Formimidoylthienamycin 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))- Imipemide Anhydrous, Imipenem MK0787
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AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
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|
cui |
C0020933 C0886855 C0729073
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|
DC |
1
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|
definition |
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
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DX |
19890101
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HN |
89
|
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Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
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Inverse of RB |
Q20IM7HE75 71OTZ9ZE0A 0
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isa | ||
Machine permutation |
89
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Mapped from |
http://purl.bioontology.org/ontology/MESH/C550742 http://purl.bioontology.org/ontology/MESH/C000633884 |
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MDA |
19880603
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|
MMR |
20160531
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MN |
D03.633.100.300.124.300.500 D02.065.589.099.124.300.500
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|
notation |
D015378
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PA |
D000900
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prefLabel |
Imipenem
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RR |
Q20IM7HE75 74431-23-5 (Imipenem)
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TERMUI |
T839048 T045343 T359724 T045340 T045341 T045342 T045344
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TH |
NLM (1999) FDA SRS (2014) UNK (19XX) INN (19XX) NLM (2014) USP (19XX) BAN (19XX) USAN (1983)
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tui |
T109 T195 T121
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subClassOf |
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