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Medical Subject Headings
| Preferred Name | Irinotecan | |
| Synonyms |
SN3811 CPT 11 Camptothecin-11 SN-38-11 7 Ethyl 10 hydroxycamptothecin Irinotecan Hydrochloride 7-Ethyl-10-hydroxycamptothecin Camptosar (1,4'-Bipiperidine)-1'-carboxylic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester SN-38 Irrinotecan Camptothecin 11 CPT11 SN 38 11 CPT-11 SN 38 NK012 Compound |
|
| Definitions |
A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS. |
|
| ID |
http://purl.bioontology.org/ontology/MESH/D000077146 |
|
| altLabel |
SN3811 CPT 11 Camptothecin-11 SN-38-11 7 Ethyl 10 hydroxycamptothecin Irinotecan Hydrochloride 7-Ethyl-10-hydroxycamptothecin Camptosar (1,4'-Bipiperidine)-1'-carboxylic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester SN-38 Irrinotecan Camptothecin 11 CPT11 SN 38 11 CPT-11 SN 38 NK012 Compound
|
|
| AQL |
AA AD AE AG AI AN BL CF CH CL CS EC HI IM IP ME PD PK PO RE SD ST TO TU UR
|
|
| cui |
C0142711 C4317169 C0594375 C0099808 C0142710 C0701188 C4760648 C2350197 C0123931
|
|
| DC |
1
|
|
| definition |
A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.
|
|
| DX |
20190101
|
|
| HN |
2019 (1987)
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|
| Inverse of AQ |
http://purl.bioontology.org/ontology/MESH/Q000097 http://purl.bioontology.org/ontology/MESH/Q000627 http://purl.bioontology.org/ontology/MESH/Q000493 http://purl.bioontology.org/ontology/MESH/Q000494 http://purl.bioontology.org/ontology/MESH/Q000276 http://purl.bioontology.org/ontology/MESH/Q000138 http://purl.bioontology.org/ontology/MESH/Q000134 http://purl.bioontology.org/ontology/MESH/Q000266 http://purl.bioontology.org/ontology/MESH/Q000378 http://purl.bioontology.org/ontology/MESH/Q000008 http://purl.bioontology.org/ontology/MESH/Q000009 http://purl.bioontology.org/ontology/MESH/Q000031 http://purl.bioontology.org/ontology/MESH/Q000032 http://purl.bioontology.org/ontology/MESH/Q000037 http://purl.bioontology.org/ontology/MESH/Q000191 http://purl.bioontology.org/ontology/MESH/Q000302 http://purl.bioontology.org/ontology/MESH/Q000145 http://purl.bioontology.org/ontology/MESH/Q000592 http://purl.bioontology.org/ontology/MESH/Q000737 http://purl.bioontology.org/ontology/MESH/Q000819 http://purl.bioontology.org/ontology/MESH/Q000506 http://purl.bioontology.org/ontology/MESH/Q000633 http://purl.bioontology.org/ontology/MESH/Q000600 |
|
| Inverse of RB |
0H43101T0J 042LAQ1IIS 7673326042 0
|
|
| isa | ||
| LT |
TRD
|
|
| Machine permutation |
2019; IRINOTECAN was indexed under CAMPTOTHECIN 1987-2018
|
|
| Mapped from | ||
| MDA |
20180709
|
|
| MMR |
20180702
|
|
| MN |
D03.132.151.425
|
|
| notation |
D000077146
|
|
| PA |
D059004
|
|
| prefLabel |
Irinotecan
|
|
| RR |
0H43101T0J 042LAQ1IIS
|
|
| TERMUI |
T177541 T000938388 T177533 T000936943 T000938390 T000936941 T177528 T177540 T177529 T177532 T177531 T177530 T000936939
|
|
| TH |
NLM (2008) FDA SRS (2017) NLM (1987) NLM (2001) USAN (19XX) INN (19XX)
|
|
| tui |
T109 T121
|
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |