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| Preferred Name | signal transduction | |
| Synonyms |
signal transduction by protein phosphorylation signal transduction by cis-phosphorylation signal transduction by conformational transition signal transduction by trans-phosphorylation signaling cascade signalling cascade signaling pathway signalling pathway |
|
| Definitions |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. |
|
| ID |
http://purl.obolibrary.org/obo/GO_0007165 |
|
| comment |
Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.
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| database_cross_reference |
Wikipedia:Signal_transduction
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|
| definition |
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
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| has_alternative_id |
GO:0023033 GO:0023014 GO:0023016 GO:0023015 GO:0023045
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|
| has_narrow_synonym |
signal transduction by protein phosphorylation signal transduction by cis-phosphorylation signal transduction by conformational transition signal transduction by trans-phosphorylation signaling cascade signalling cascade
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|
| has_obo_namespace |
biological_process
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|
| has_related_synonym |
signaling pathway signalling pathway
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|
| id |
GO:0007165
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|
| imported from | ||
| in_subset |
http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_candida http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_metagenomics http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_plant http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_chembl http://purl.oboInOwllibrary.org/oboInOwl/go#goslim_aspergillus |
|
| label |
signal transduction
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|
| notation |
GO:0007165
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|
| prefLabel |
signal transduction
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|
| subClassOf | ||
| has_participant |
http://purl.obolibrary.org/obo/PR_P11274 http://purl.obolibrary.org/obo/PR_P04083 http://purl.obolibrary.org/obo/PR_P35348 http://purl.obolibrary.org/obo/PR_Q02750 http://purl.obolibrary.org/obo/PR_P08235 http://purl.obolibrary.org/obo/PR_P42684 http://purl.obolibrary.org/obo/PR_P10721 http://purl.obolibrary.org/obo/PR_O60760 http://purl.obolibrary.org/obo/PR_Q15125 http://purl.obolibrary.org/obo/PR_P07948 http://purl.obolibrary.org/obo/PR_P07333 http://purl.obolibrary.org/obo/PR_P28472 http://purl.obolibrary.org/obo/PR_Q9UM73 http://purl.obolibrary.org/obo/PR_P20309 http://purl.obolibrary.org/obo/PR_Q92731 http://purl.obolibrary.org/obo/PR_P06401 http://purl.obolibrary.org/obo/PR_P03372 http://purl.obolibrary.org/obo/PR_P11802 http://purl.obolibrary.org/obo/PR_P04150 http://purl.obolibrary.org/obo/PR_P49069 http://purl.obolibrary.org/obo/PR_P09038 http://purl.obolibrary.org/obo/PR_P12931 http://purl.obolibrary.org/obo/PR_P09619 http://purl.obolibrary.org/obo/PR_P10275 http://purl.obolibrary.org/obo/PR_P30530 http://purl.obolibrary.org/obo/PR_O75469 http://purl.obolibrary.org/obo/PR_P11229 http://purl.obolibrary.org/obo/PR_P17405 http://purl.obolibrary.org/obo/PR_P08173 http://purl.obolibrary.org/obo/PR_Q16539 |
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