Human Reference Atlas

Last uploaded: June 14, 2024
Preferred Name

serous membrane
Synonyms

serosa

wall of serous sac

tunica serosa

Definitions

Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer.

ID

http://purl.obolibrary.org/obo/UBERON_0000042

altLabel

serosa

wall of serous sac

tunica serosa

contributor

https://github.com/cmungall

definition

Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer.

depiction

http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png

http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png

external_definition

A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]

a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]

external_ontology_notes

in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA.

has exact synonym

wall of serous sac

tunica serosa

has related synonym

serosa

has_obo_namespace

uberon

id

UBERON:0000042

in_subset

http://purl.obolibrary.org/obo/uberon/core#vertebrate_core

http://purl.obolibrary.org/obo/uberon/core#uberon_slim

label

serous membrane

notation

UBERON:0000042

part_of

http://purl.obolibrary.org/obo/UBERON_0000060

http://purl.obolibrary.org/obo/NCBITaxon_6072

prefLabel

serous membrane

treeView

http://purl.obolibrary.org/obo/UBERON_0000060

http://purl.obolibrary.org/obo/NCBITaxon_6072

xRef

GAID:19

MESH:D012704

UMLS:C0036760

Wikipedia:Serous_membrane

SCTID:362878009

ZFA:0005425

TAO:0005425

FMA:9581

NCIT:C13169

subClassOf

http://purl.obolibrary.org/obo/UBERON_0000481

http://purl.obolibrary.org/obo/UBERON_0004120

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Delete Mapping To Ontology Source
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http://purl.obolibrary.org/obo/ZFA_0005425 ZFA LOOM
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http://radlex.org/RID/RID28467 RADLEX LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#11224 OCHV LOOM