Human Reference Atlas

Last uploaded: June 14, 2024
Preferred Name

Interstitial cells of Cajal
Synonyms

intestinal pacemaker cell

ICC

Definitions

This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. Some argue this cell type is of mesenchymal origin.

ID

http://purl.obolibrary.org/obo/CL_0002088

comment

Some argue this cell type is of mesenchymal origin.

altLabel

intestinal pacemaker cell

ICC

ccf_ct_isa

http://purl.obolibrary.org/obo/CL_0000000

ccf_is_provisional

false

ccf_located_in

http://purl.obolibrary.org/obo/UBERON_0000059

http://purl.obolibrary.org/obo/UBERON_0012489

http://purl.obolibrary.org/obo/UBERON_0001153

http://purl.obolibrary.org/obo/UBERON_0001159

http://purl.obolibrary.org/obo/UBERON_0001154

http://purl.obolibrary.org/obo/UBERON_0001157

http://purl.obolibrary.org/obo/UBERON_0001156

http://purl.obolibrary.org/obo/UBERON_0001158

http://purl.obolibrary.org/obo/UBERON_0004927

http://purl.org/sig/ont/fma/fma14966

http://purl.obolibrary.org/obo/UBERON_0000159

http://purl.obolibrary.org/obo/UBERON_0022276

http://purl.obolibrary.org/obo/UBERON_0022277

http://purl.obolibrary.org/obo/UBERON_0000569

http://purl.obolibrary.org/obo/UBERON_0001052

http://purl.obolibrary.org/obo/UBERON_0002108

http://purl.obolibrary.org/obo/UBERON_0003331

https://purl.org/ccf/ASCTB-TEMP_muscularis-externa

http://purl.obolibrary.org/obo/UBERON_0002439

https://purl.org/ccf/ASCTB-TEMP_circular-longitudinal-muscle

http://purl.obolibrary.org/obo/UBERON_0002115

http://purl.obolibrary.org/obo/UBERON_0012377

http://purl.obolibrary.org/obo/UBERON_0003329

ccf_pref_label

Interstitial cells of Cajal

interstitial cell of Cajal

contributor

https://orcid.org/0000-0003-1980-3228

creation date

2010-07-22T03:26:00Z

definition

This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.

has exact synonym

intestinal pacemaker cell

ICC

in_subset

http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas

http://purl.obolibrary.org/obo/cl#cellxgene_subset

isDefinedBy

http://purl.obolibrary.org/obo/cl.owl

label

interstitial cell of Cajal

prefixIRI

CL:0002088

prefLabel

Interstitial cells of Cajal

interstitial cell of Cajal

xRef

FMA:86573

BTO:0003914

subClassOf

http://purl.obolibrary.org/obo/CL_0000710

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CL_0002088 CL SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 UBERON SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 FOVT SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 CHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 RBO SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 PCL SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 NIFDYS SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 GO-PLUS SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 BERO SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 HHEAR SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 UPHENO SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 ECAO SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 AISM SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 NMDCO SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 OBA SAME_URI
http://purl.obolibrary.org/obo/CL_0002088 CL LOOM
http://purl.obolibrary.org/obo/CL_0002088 UBERON LOOM
http://purl.obolibrary.org/obo/CL_0002088 FOVT LOOM
http://purl.obolibrary.org/obo/CL_0002088 CHEAR LOOM
http://purl.obolibrary.org/obo/CL_0002088 RBO LOOM
http://purl.obolibrary.org/obo/CL_0002088 PCL LOOM
http://purl.obolibrary.org/obo/CL_0002088 NIFDYS LOOM
http://purl.obolibrary.org/obo/CL_0002088 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CL_0002088 HHEAR LOOM
http://purl.obolibrary.org/obo/CL_0002088 UPHENO LOOM
http://purl.obolibrary.org/obo/CL_0002088 NIFSTD LOOM
http://purl.obolibrary.org/obo/CL_0002088 ECAO LOOM
http://purl.obolibrary.org/obo/CL_0002088 AISM LOOM
http://purl.obolibrary.org/obo/CL_0002088 NMDCO LOOM
http://purl.obolibrary.org/obo/CL_0002088 OBA LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C32871 NCIT LOOM
http://purl.org/obo/owlapi/fma#FMA_86573 BIOMODELS LOOM
http://purl.org/sig/ont/fma/fma86573 FMA LOOM
http://purl.org/obo/owl/CL#CL_0002088 BIOMODELS LOOM
http://purl.bioontology.org/ontology/CSP/5006-0020 CRISP LOOM
http://purl.obolibrary.org/obo/BTO_0003914 DTO LOOM
http://purl.obolibrary.org/obo/BTO_0003914 BTO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/1156991003 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/NCIT_C32871 BERO LOOM