Preferred Name |
keratinocyte |
|
Synonyms |
malpighian cell keratinized cell of epidermis |
|
Definitions |
Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
|
ID |
http://purl.obolibrary.org/obo/CL_0000312 |
|
comment |
Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. |
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ccf_ct_isa | ||
ccf_is_provisional |
false |
|
ccf_located_in |
http://purl.obolibrary.org/obo/UBERON_0000059 http://purl.obolibrary.org/obo/UBERON_0008198 http://purl.obolibrary.org/obo/UBERON_0002097 http://purl.obolibrary.org/obo/UBERON_0002069 http://purl.obolibrary.org/obo/UBERON_0002067 http://purl.obolibrary.org/obo/UBERON_0001245 |
|
ccf_pref_label |
keratinocyte Keratinocyte (Granular) |
|
definition |
An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
|
has exact synonym |
malpighian cell keratinized cell of epidermis |
|
in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
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isDefinedBy | ||
label |
keratinocyte |
|
part_of | ||
prefixIRI |
CL:0000312 |
|
prefLabel |
keratinocyte Keratinocyte (Granular) |
|
present in taxon | ||
treeView | ||
xRef |
CALOHA:TS-0500 FMA:62879 ZFA:0009158 BTO:0000667 |
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subClassOf |