loading...| Preferred Name |
Neural tube defect |
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| Synonyms |
Abnormality of neural tube closure |
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| Definitions |
A neural tube defect arises when the neural tube, the embryonic precursor of the brain and spinal cord, fails to close during neurulation. The cranial region (anencephaly) or the low spine (open spina bifida; myelomeningocele) are most commonly affected although, in the severe NTD craniorachischisis, almost the entire neural tube remains open, from midbrain to low spine. |
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| ID |
http://purl.obolibrary.org/obo/HP_0045005 |
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| creator | ||
| database_cross_reference |
UMLS:C0027794 MSH:D009436 SNOMEDCT_US:253098009 |
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| definition |
A neural tube defect arises when the neural tube, the embryonic precursor of the brain and spinal cord, fails to close during neurulation. The cranial region (anencephaly) or the low spine (open spina bifida; myelomeningocele) are most commonly affected although, in the severe NTD craniorachischisis, almost the entire neural tube remains open, from midbrain to low spine. |
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| has_exact_synonym |
Abnormality of neural tube closure |
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| has_obo_namespace |
human_phenotype |
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| id |
HP:0045005 |
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| label |
Neural tube defect |
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| notation |
HP:0045005 |
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| prefLabel |
Neural tube defect |
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| treeView | ||
| subClassOf |