Human Phenotype Ontology

Last uploaded: August 13, 2024
Preferred Name

Nesidioblastosis
Synonyms
Definitions

An abnormality of pancreatic beta cells characterized by a proliferation of abnormal beta cells throughout the entire pancreas, with enlarged islet size and number (hypertrophic islets), increased periductular islets, enlarged beta-cell nuclei and abundant clear cytoplasm. Occasionally beta cells with pleomorphic nuclei, ductuloinsular complexes, and neoformation of islets from ducts are observed.

ID

http://purl.obolibrary.org/obo/HP_0034346

dc_date

2022-09-04T14:58:56Z

definition

An abnormality of pancreatic beta cells characterized by a proliferation of abnormal beta cells throughout the entire pancreas, with enlarged islet size and number (hypertrophic islets), increased periductular islets, enlarged beta-cell nuclei and abundant clear cytoplasm. Occasionally beta cells with pleomorphic nuclei, ductuloinsular complexes, and neoformation of islets from ducts are observed.

has_obo_namespace

human_phenotype

id

HP:0034346

label

Nesidioblastosis

notation

HP:0034346

prefLabel

Nesidioblastosis

terms_creator

https://orcid.org/0000-0002-0736-9199

treeView

http://purl.obolibrary.org/obo/HP_0012090

subClassOf

http://purl.obolibrary.org/obo/HP_0012090

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