Human Phenotype Ontology

Last uploaded: August 13, 2024
Preferred Name

Acute respiratory distress syndrome
Synonyms

ARDS

Definitions

Acute respiratory distress syndrome (ARDS) is defined as an acute disorder that starts within seven days of the inciting event and is characterized by bilateral lung infiltrates and severe progressive hypoxemia in the absence of any evidence of cardiogenic pulmonary edema. ARDS is defined by the patient's oxygen in arterial blood (PaO2) to the fraction of the oxygen in the inspired air (FiO2). These patients have a PaO2/FiO2 ratio of less than 300. Acute respiratory distress syndrome (ARDS) is a life-threatening condition of seriously ill patients, characterized by poor oxygenation, pulmonary infiltrates, and acuity of onset. On a microscopic level, the disorder is associated with capillary endothelial injury and diffuse alveolar damage. Once ARDS develops, patients usually have varying degrees of pulmonary artery vasoconstriction and may subsequently develop pulmonary hypertension. ARDS carries a high mortality, and few effective therapeutic modalities exist to combat this condition. ARDS can be observed as a complication of many diseases including pulmonary infection or aspiration, sepsis, trauma, massive transfusion, drowning, drug overdose, fat embolism, inhalation of toxic fumes, and pancreatitis.

ID

http://purl.obolibrary.org/obo/HP_0033677

comment

Acute respiratory distress syndrome (ARDS) is a life-threatening condition of seriously ill patients, characterized by poor oxygenation, pulmonary infiltrates, and acuity of onset. On a microscopic level, the disorder is associated with capillary endothelial injury and diffuse alveolar damage. Once ARDS develops, patients usually have varying degrees of pulmonary artery vasoconstriction and may subsequently develop pulmonary hypertension. ARDS carries a high mortality, and few effective therapeutic modalities exist to combat this condition. ARDS can be observed as a complication of many diseases including pulmonary infection or aspiration, sepsis, trauma, massive transfusion, drowning, drug overdose, fat embolism, inhalation of toxic fumes, and pancreatitis.

dc_date

2021-03-03T20:15:47Z

definition

Acute respiratory distress syndrome (ARDS) is defined as an acute disorder that starts within seven days of the inciting event and is characterized by bilateral lung infiltrates and severe progressive hypoxemia in the absence of any evidence of cardiogenic pulmonary edema. ARDS is defined by the patient's oxygen in arterial blood (PaO2) to the fraction of the oxygen in the inspired air (FiO2). These patients have a PaO2/FiO2 ratio of less than 300.

has_exact_synonym

ARDS

has_obo_namespace

human_phenotype

id

HP:0033677

label

Acute respiratory distress syndrome

notation

HP:0033677

prefLabel

Acute respiratory distress syndrome

terms_creator

https://orcid.org/0000-0002-0736-9199

treeView

http://purl.obolibrary.org/obo/HP_0004887

subClassOf

http://purl.obolibrary.org/obo/HP_0004887

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/HP_0033677 UPHENO SAME_URI
http://purl.obolibrary.org/obo/HP_0033677 GENEPIO SAME_URI
http://purl.obolibrary.org/obo/HP_0033677 UPHENO LOOM
http://purl.bioontology.org/ontology/LNC/LA28203-0 LOINC LOOM
http://purl.org/vodan/whocovid19crfsemdatamodel/Acute_Respiratory_Distress_Syndrome COVIDCRFRAPID LOOM
http://vocab.vodan-totafrica.info/vodana-terms/vdiseases/CB00 VODANADISEASES LOOM
http://www.ebi.ac.uk/efo/EFO_1000637 CCONT LOOM
http://www.ebi.ac.uk/efo/EFO_1000637 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_1000637 EFO LOOM
http://www.ebi.ac.uk/efo/EFO_1000637 VIDO LOOM
http://www.ebi.ac.uk/efo/EFO_1000637 IDO-COVID-19 LOOM
http://purl.obolibrary.org/obo/ICDO_0000206 ICDO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/67782005 PNADO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/67782005 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/ICD10CM/J80 NLMVS LOOM
http://purl.bioontology.org/ontology/ICD10CM/J80 ICD10CM LOOM
http://www.mskcc.org/ontologies/2013/03/sae.owl#Acute_Respiratory_Distress_Syndrome SSE LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3353 NCIT LOOM
rgo:14326 GAMUTS LOOM
http://localhost/plosthes.2017-1#1540463 PLOSTHES LOOM
http://purl.obolibrary.org/obo/DOID_11394 HOIP LOOM
http://purl.obolibrary.org/obo/HP_0033677 GENEPIO LOOM
http://purl.bioontology.org/ontology/MEDDRA/10001052 MEDDRA LOOM
http://purl.obolibrary.org/obo/MONDO_0006502 OOSTT LOOM
http://purl.obolibrary.org/obo/MONDO_0006502 MONDO LOOM
http://purl.obolibrary.org/obo/MONDO_0006502 DOVES LOOM
http://purl.obolibrary.org/obo/MONDO_0006502 GENEPIO LOOM
http://purl.obolibrary.org/obo/NCIT_C3353 BERO LOOM
http://purl.obolibrary.org/obo/NCIT_C3353 GENEPIO LOOM
http://purl.obolibrary.org/obo/NCIT_C3353 COVIDCRFRAPID LOOM
http://purl.bioontology.org/ontology/OMIM/MTHU056817 OMIM LOOM