Human Phenotype Ontology

Last uploaded: April 26, 2024
Preferred Name

Peptic ulcer

Synonyms

Sore in the lining of gastrointestinal tract

Definitions

Symptoms of peptic ulcer disease have limited predictive value because they are non-specific. Patients with duodenal ulcers typically feel hungry or have nocturnal abdominal pain. By contrast, patients with gastric ulcers have postprandial abdominal pain, nausea, vomiting, and weight loss. Patients with untreated peptic ulcer disease typically have relapsing symptoms because of spontaneous healing and relapse while the causal factor (eg, H pylori infection or NSAID use) persists. The term peptic ulcer refers to acid peptic injury of the digestive tract, resulting in mucosal break reaching the submucosa. Peptic ulcers are usually located in the stomach or proximal duodenum, but they can also be found in the esophagus or Meckel's diverticulum. Infection with Helicobacter pylori and the use of non steroidal antiinflammatory drugs (NSAIDs) or aspirin are the main risk factors of both gastric and duodenal peptic ulcers.

ID

http://purl.obolibrary.org/obo/HP_0004398

comment

Symptoms of peptic ulcer disease have limited predictive value because they are non-specific. Patients with duodenal ulcers typically feel hungry or have nocturnal abdominal pain. By contrast, patients with gastric ulcers have postprandial abdominal pain, nausea, vomiting, and weight loss. Patients with untreated peptic ulcer disease typically have relapsing symptoms because of spontaneous healing and relapse while the causal factor (eg, H pylori infection or NSAID use) persists.

creation_date

2008-03-18T09:14:00Z

creator

https://orcid.org/0000-0002-0736-9199

database_cross_reference

SNOMEDCT_US:13200003

MSH:D010437

UMLS:C0030920

definition

The term peptic ulcer refers to acid peptic injury of the digestive tract, resulting in mucosal break reaching the submucosa. Peptic ulcers are usually located in the stomach or proximal duodenum, but they can also be found in the esophagus or Meckel's diverticulum. Infection with Helicobacter pylori and the use of non steroidal antiinflammatory drugs (NSAIDs) or aspirin are the main risk factors of both gastric and duodenal peptic ulcers.

has_exact_synonym

Sore in the lining of gastrointestinal tract

has_obo_namespace

human_phenotype

id

HP:0004398

label

Peptic ulcer

notation

HP:0004398

prefLabel

Peptic ulcer

treeView

http://purl.obolibrary.org/obo/HP_0034274

subClassOf

http://purl.obolibrary.org/obo/HP_0034274

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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/HP_0004398 EFO SAME_URI
http://purl.obolibrary.org/obo/HP_0004398 GAMUTS SAME_URI
http://purl.obolibrary.org/obo/HP_0004398 UPHENO SAME_URI
http://purl.obolibrary.org/obo/MP_0003301 MP LOOM
http://purl.obolibrary.org/obo/HP_0004398 EFO LOOM
http://purl.bioontology.org/ontology/CST/ULCER%20PEPTIC COSTART LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C06.405.469.275.800 RH-MESH LOOM
http://www.gamuts.net/entity#peptic_ulcer GAMUTS LOOM
http://purl.obolibrary.org/obo/HP_0004398 UPHENO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C3318 NCIT LOOM
http://purl.bioontology.org/ontology/MEDDRA/10034341 MEDDRA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010437 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C3318 BERO LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0030920 MEDLINEPLUS LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9452 OCHV LOOM
http://purl.bioontology.org/ontology/MESH/D010437 MESH LOOM
http://www.owl-ontologies.com/NPOntology.owl#DOID_750 NATPRO LOOM
http://www.co-ode.org/ontologies/galen#PepticUlcer GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C06.405.748.586 RH-MESH LOOM
http://purl.bioontology.org/ontology/WHO/0315 WHO-ART LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/13200003 SNOMEDCT LOOM
http://purl.jp/bio/4/id/200906001259655458 IOBC LOOM
http://radlex.org/RID/RID5039 RADLEX LOOM
http://www.phoc.org.cn/pmo/class/PMO_00036892 PMAPP-PMO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Peptic_Ulcer CSEO LOOM
http://purl.bioontology.org/ontology/ICPC2P/D86002 ICPC2P LOOM
http://purl.bioontology.org/ontology/CSP/1248-6649 CRISP LOOM
http://purl.obolibrary.org/obo/MP_0003301 UPHENO LOOM
http://purl.obolibrary.org/obo/MP_0003301 CHIRO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C06.405.608 RH-MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0011431 OMIT LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClassfed57fe5_1b24_44fc_a0fd_f4f3db5b303c WWECA LOOM
http://www.gamuts.net/entity#peptic_ulcer GAMUTS REST