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Human Phenotype Ontology
Last uploaded:
August 13, 2024
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| Preferred Name | Gliosis | |
| Synonyms |
Excess astrocytes in brain Cerebral gliosis |
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| Definitions |
Gliosis is the focal proliferation of glial cells in the central nervous system. Gliosis generally occurs as a response to tissue damage. Gliosis appears bright on T2 scans upon magnetic resonance imaging, unlike encephalomalacia which follows CSF signal on all sequences. Glial cells, the non-neuronal component of the central nervous system, are divided into microglia and macroglia. The latter are in turn divided into astrocytes, oligodendrocytes, and ependymal cells. The astrocytes and the microglia are the glial cells predominantly responsible for tissue response to injury. |
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| ID |
http://purl.obolibrary.org/obo/HP_0002171 |
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| comment |
Gliosis generally occurs as a response to tissue damage. Gliosis appears bright on T2 scans upon magnetic resonance imaging, unlike encephalomalacia which follows CSF signal on all sequences. Glial cells, the non-neuronal component of the central nervous system, are divided into microglia and macroglia. The latter are in turn divided into astrocytes, oligodendrocytes, and ependymal cells. The astrocytes and the microglia are the glial cells predominantly responsible for tissue response to injury.
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| database_cross_reference |
SNOMEDCT_US:359580009 SNOMEDCT_US:81415000 UMLS:C0017639
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| definition |
Gliosis is the focal proliferation of glial cells in the central nervous system.
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| has_exact_synonym |
Excess astrocytes in brain Cerebral gliosis
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| has_obo_namespace |
human_phenotype
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| id |
HP:0002171
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| label |
Gliosis
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| notation |
HP:0002171
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| prefLabel |
Gliosis
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| treeView | ||
| subClassOf |
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