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Human Phenotype Ontology
Last uploaded:
December 11, 2024
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| Preferred Name | Macrocytic anemia | |
| Synonyms |
Macrocytic anaemia |
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| Definitions |
A type of anemia characterized by increased size of erythrocytes with increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH). The causes of macrocytosis can be broadly classified as megaloblastic and nonmegaloblastic. Megaloblastic processes are characterized on the peripheral smear by macroovalocytes and hypersegmented neutrophils, which are absent in nonmegaloblastic macrocytic processes. Nonmegaloblastic processes have round macrocytes or macroreticulocytes. |
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| ID |
http://purl.obolibrary.org/obo/HP_0001972 |
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| comment |
The causes of macrocytosis can be broadly classified as megaloblastic and nonmegaloblastic. Megaloblastic processes are characterized on the peripheral smear by macroovalocytes and hypersegmented neutrophils, which are absent in nonmegaloblastic macrocytic processes. Nonmegaloblastic processes have round macrocytes or macroreticulocytes.
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| database_cross_reference |
SNOMEDCT_US:83414005 UMLS:C0002886
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| definition |
A type of anemia characterized by increased size of erythrocytes with increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).
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| has_exact_synonym |
Macrocytic anaemia
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| has_obo_namespace |
human_phenotype
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| id |
HP:0001972
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| label |
Macrocytic anemia
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| notation |
HP:0001972
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| prefLabel |
Macrocytic anemia
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| treeView | ||
| subClassOf |
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