loading...| Preferred Name |
ethambutol |
|
| Synonyms |
(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol |
|
| Definitions |
An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4877 |
|
| database cross reference |
PMID:10891117 PMID:19524332 PMID:17888665 Beilstein:6312870 PMID:14695841 PMID:3934384 Drug_Central:1073 PMID:14698152 CAS:74-55-5 PMID:17331717 PMID:12182855 PMID:16870429 PMID:19648006 PMID:10649975 DrugBank:DB00330 Reaxys:6312870 PMID:15225698 PMID:17210775 PMID:10966749 PMID:17276683 PMID:17851083 PMID:16759086 PMID:17562368 PMID:17239593 PMID:16005211 PMID:17315960 |
|
| definition |
An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35703 |
|
| has_exact_synonym |
(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol Ethambutol |
|
| has_related_synonym |
(+)-S,S-ethambutol ethambutol S,S-Ethambutol etambutol (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine ethambutolum (+)-ethambutol (+)-2,2'-(ethylenediimino)di-1-butanol (2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol (S,S)-ethambutol EMB |
|
| label |
ethambutol |
|
| prefixIRI |
CHEBI:4877 |
|
| prefLabel |
ethambutol |
|
| subClassOf |