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Hearing Impairment Ontology
Last uploaded:
October 31, 2019
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| Preferred Name | Insertion | |
| Synonyms |
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| Definitions |
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt genetic translation of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation. |
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| ID |
http://purl.obolibrary.org/obo/HIO_0000449 |
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| description |
Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt genetic translation of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.
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| created_by |
Jade Hotchkiss
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| creation_date |
2019-08-29T20:57:03.819768Z
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| database cross reference |
MESH:D016254
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| definition source | ||
| existence in other ontologies |
Sufficient
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| hasExactSynonym |
Gene Insertion Insertion Mutation
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| label |
Insertion
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| prefixIRI |
HIO:0000449
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| prefLabel |
Insertion
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| subClassOf |
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