loading...| Preferred Name | Presynaptic phase of homologous DNA pairing and strand exchange | |
| Synonyms |
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| Definitions |
The presynaptic phase of homologous DNA pairing and strand exchange begins with the displacement of RPA from ssDNA, followed by the association of RAD51 with BRCA2, formation of RAD52 heptameric ring structure complexes on ssDNA, association of RAD52 with the RPA complex, association of RAD52 with ssDNA at resected ends of double-strand break and assembly of the RAD51-ssDNA nucleoprotein complex. |
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| ID |
http://purl.obolibrary.org/obo/HINO_0016489 |
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| comment |
The presynaptic phase of homologous DNA pairing and strand exchange begins with the displacement of RPA from ssDNA, followed by the association of RAD51 with BRCA2, formation of RAD52 heptameric ring structure complexes on ssDNA, association of RAD52 with the RPA complex, association of RAD52 with ssDNA at resected ends of double-strand break and assembly of the RAD51-ssDNA nucleoprotein complex. |
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| definition source |
Reactome, http://www.reactome.org |
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| label |
Presynaptic phase of homologous DNA pairing and strand exchange |
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| located_in | ||
| prefixIRI |
HINO:0016489 |
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| prefLabel |
Presynaptic phase of homologous DNA pairing and strand exchange |
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| seeAlso |
Reactome Database ID Release 4376003 ReactomeREACT_408 |
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| subClassOf | ||
| has_part |
http://purl.obolibrary.org/obo/HINO_0025050 http://purl.obolibrary.org/obo/HINO_0025051 http://purl.obolibrary.org/obo/HINO_0016487 |