Preferred Name | Assembly of the RAD51-ssDNA nucleoprotein complex | |
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Definitions |
The RAD51-ssDNA nucleoprotein filament is a right-hand helical nucleoprotein filament referred to as the presynaptic filament. This nucleoprotein complex contains a binding site for the double-stranded homologous DNA molecule with which it interacts during strand exchange. Loading of RAD51 onto ssDNA is thought to be facilitated by recombination mediator RAD52 (McIlwraith et al., 2000), RAD51 paralogs: RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3 (Sigurdsson et al., 2001), by the association of RAD52 with ssDNA (Parsons et al., 2000) and by the association of RAD51 with BRCA2 (Tarsounas et al., 2003). Authored: Matthews, L, 2003-09-10 06:00:00 |
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ID |
http://purl.obolibrary.org/obo/HINO_0016487 |
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comment |
The RAD51-ssDNA nucleoprotein filament is a right-hand helical nucleoprotein filament referred to as the presynaptic filament. This nucleoprotein complex contains a binding site for the double-stranded homologous DNA molecule with which it interacts during strand exchange. Loading of RAD51 onto ssDNA is thought to be facilitated by recombination mediator RAD52 (McIlwraith et al., 2000), RAD51 paralogs: RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3 (Sigurdsson et al., 2001), by the association of RAD52 with ssDNA (Parsons et al., 2000) and by the association of RAD51 with BRCA2 (Tarsounas et al., 2003). Authored: Matthews, L, 2003-09-10 06:00:00 |
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definition source |
Pubmed11751636 Reactome, http://www.reactome.org Pubmed12606939 Pubmed11459989 Pubmed10921897 Pubmed11080452 |
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label |
Assembly of the RAD51-ssDNA nucleoprotein complex |
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located_in | ||
prefixIRI |
HINO:0016487 |
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prefLabel |
Assembly of the RAD51-ssDNA nucleoprotein complex |
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seeAlso |
Reactome Database ID Release 4376000 GENE ONTOLOGYGO:0000730 ReactomeREACT_2141 |
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subClassOf | ||
has_part |
http://purl.obolibrary.org/obo/HINO_0025057 |