Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Assembly of the RAD51-ssDNA nucleoprotein complex
Synonyms
Definitions

The RAD51-ssDNA nucleoprotein filament is a right-hand helical nucleoprotein filament referred to as the presynaptic filament. This nucleoprotein complex contains a binding site for the double-stranded homologous DNA molecule with which it interacts during strand exchange. Loading of RAD51 onto ssDNA is thought to be facilitated by recombination mediator RAD52 (McIlwraith et al., 2000), RAD51 paralogs: RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3 (Sigurdsson et al., 2001), by the association of RAD52 with ssDNA (Parsons et al., 2000) and by the association of RAD51 with BRCA2 (Tarsounas et al., 2003). Authored: Matthews, L, 2003-09-10 06:00:00

ID

http://purl.obolibrary.org/obo/HINO_0016487

comment

The RAD51-ssDNA nucleoprotein filament is a right-hand helical nucleoprotein filament referred to as the presynaptic filament. This nucleoprotein complex contains a binding site for the double-stranded homologous DNA molecule with which it interacts during strand exchange. Loading of RAD51 onto ssDNA is thought to be facilitated by recombination mediator RAD52 (McIlwraith et al., 2000), RAD51 paralogs: RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3 (Sigurdsson et al., 2001), by the association of RAD52 with ssDNA (Parsons et al., 2000) and by the association of RAD51 with BRCA2 (Tarsounas et al., 2003).

Authored: Matthews, L, 2003-09-10 06:00:00

definition source

Pubmed11751636

Reactome, http://www.reactome.org

Pubmed12606939

Pubmed11459989

Pubmed10921897

Pubmed11080452

label

Assembly of the RAD51-ssDNA nucleoprotein complex

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0016487

prefLabel

Assembly of the RAD51-ssDNA nucleoprotein complex

seeAlso

Reactome Database ID Release 4376000

GENE ONTOLOGYGO:0000730

ReactomeREACT_2141

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

has_part

http://purl.obolibrary.org/obo/HINO_0025057

http://purl.obolibrary.org/obo/HINO_0025056

http://purl.obolibrary.org/obo/HINO_0025048

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http://scai.fraunhofer.de/PWDICT#ID2078 PTS LOOM