Preferred Name | bicalutamide | |
Synonyms |
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Definitions |
A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism. |
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ID |
http://purl.obolibrary.org/obo/CHEBI_3090 |
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ATC Code |
L02BB03 |
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ChEBI ID | ||
definition |
A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism. |
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has database cross reference | ||
label |
bicalutamide |
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MeSH Descriptor ID | ||
NCI Thesaurus ID | ||
prefixIRI |
CHEBI:3090 |
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prefLabel |
bicalutamide |
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SNOMED CT Identifier | ||
subClassOf |