loading...| Preferred Name |
tropical spastic paraparesis |
|
| Synonyms |
familial spastic paraparesis, HTLV-1-associated Human T-cell leukaemia virus type 1 associated myelopathy/tropical spastic paraparesis Human T-cell leukemia virus type 1 associated myelopathy/tropical spastic paraparesis HTLV-1 associated myelopathy/tropical spastic paraparesis tropical spastic paraparesis (formerly) myelopathy, HTLV-1-associated ham Paraparesis, Tropical Spastic HTLV-associated myelopathy tropical spastic paraplegia HTLV-1-associated myelopathy/tropical spastic paraparesis Tropical spastic paralysis Human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis Tropical spastic paraplegia tropical spastic paraparesis Human T-lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis tropical spastic paralysis TSP ham/TSP |
|
| Definitions |
A viral infectious disease that results_in inflammation located_in spinal cord, has_material_basis_in Human T-lymphotropic virus 1, which is transmitted_by sexual contact, and transmitted_by breast feeding. The infection has_symptom spastic weakness of both legs, has_symptom muscle stiffness, has_symptom sensory disturbance, and has_symptom spasms. Tropical spastic paraparesis is a chronic systemic immune-mediated inflammatory myeloneuropathy, more frequently reported in women than in men, that usually presents in adulthood with slowly progressive spastic paraparesis of the lower limbs, bladder and bowel dysfunction, and sensory disturbances in the lower extremities (e.g. paresthesia and dysesthesia) and that is associated with a human T-cell lymphotropic virus type 1 (HTLV-1) infection. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0007527 |
|
| closeMatch | ||
| database_cross_reference |
UMLS:C0030481 Orphanet:289326 NANDO:1200206 icd11.foundation:1043229589 MedDRA:10044696 MESH:D015493 MeSH:D015493 OMIM:159580 ICD9:323.01 MedDRA:10067606 SCTID:714279000 DOID:321 GARD:8208 MONDO:0008039 |
|
| definition |
A viral infectious disease that results_in inflammation located_in spinal cord, has_material_basis_in Human T-lymphotropic virus 1, which is transmitted_by sexual contact, and transmitted_by breast feeding. The infection has_symptom spastic weakness of both legs, has_symptom muscle stiffness, has_symptom sensory disturbance, and has_symptom spasms. Tropical spastic paraparesis is a chronic systemic immune-mediated inflammatory myeloneuropathy, more frequently reported in women than in men, that usually presents in adulthood with slowly progressive spastic paraparesis of the lower limbs, bladder and bowel dysfunction, and sensory disturbances in the lower extremities (e.g. paresthesia and dysesthesia) and that is associated with a human T-cell lymphotropic virus type 1 (HTLV-1) infection. |
|
| exactMatch |
http://purl.obolibrary.org/obo/DOID_321 http://identifiers.org/mesh/D015493 http://purl.obolibrary.org/obo/Orphanet_289326 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
Paraparesis, Tropical Spastic HTLV-associated myelopathy tropical spastic paraplegia HTLV-1-associated myelopathy/tropical spastic paraparesis Tropical spastic paralysis Human T-lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis Tropical spastic paraplegia tropical spastic paraparesis Human T-lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis tropical spastic paralysis TSP ham/TSP |
|
| has_related_synonym |
familial spastic paraparesis, HTLV-1-associated Human T-cell leukaemia virus type 1 associated myelopathy/tropical spastic paraparesis Human T-cell leukemia virus type 1 associated myelopathy/tropical spastic paraparesis HTLV-1 associated myelopathy/tropical spastic paraparesis tropical spastic paraparesis (formerly) myelopathy, HTLV-1-associated ham |
|
| id |
EFO:0007527 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disease |
|
| label |
tropical spastic paraparesis |
|
| notation |
EFO:0007527 |
|
| preferred label |
tropical spastic paraparesis |
|
| prefLabel |
tropical spastic paraparesis |
|
| term editor |
Sirarat Sarntivijai |
|
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0020010 http://www.ebi.ac.uk/efo/EFO_0009488 |