loading...| Preferred Name | anaplastic astrocytoma | |
| Synonyms |
grade III astrocytoma grade III astrocytic tumor grade III astrocytic neoplasm grade III astrocytic tumour anaplastic astrocytoma malignant astrocytoma astrocytoma, anaplastic, malignant |
|
| Definitions |
Anaplastic astrocytoma is a rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0002499 |
|
| closeMatch |
http://identifiers.org/meddra/10002224 |
|
| database_cross_reference |
UMLS:C0334579 ONCOTREE:AASTR MedDRA:10002224 MEDGEN:137784 EFO:0002499 MedDRA:10060971 MONDO:0016684 Orphanet:251589 ICDO:9401/3 GARD:0005860 NANDO:2200086 ICD10:C71.9 DOID:3078 GARD:5860 NCIT:C9477 NORD:769 |
|
| definition |
Anaplastic astrocytoma is a rare, high-grade, malignant glial tumor, histologically characterized by abundance of pleomorphic astrocytes and multiple mitotic figures, often associated with diffuse infiltration of the surrounding tissue, considerable edema and mass effect and involvement of the contralateral brain. Depending on the primary localization of the tumor, patients can present with signs of raised intracranial pressure (headache, vomiting, papilledema), seizures, progressive neurological deficits, and/or behavioral changes. The tumor is most commonly localized in the frontal and temporal lobes, brain stem and spinal cord. |
|
| exactMatch |
http://linkedlifedata.com/resource/umls/id/C0334579 http://identifiers.org/meddra/10002224 http://purl.obolibrary.org/obo/NCIT_C9477 http://identifiers.org/meddra/10060971 http://identifiers.org/medgen/137784 http://purl.obolibrary.org/obo/EFO_0002499 |
|
| has_exact_synonym |
grade III astrocytoma grade III astrocytic tumor grade III astrocytic neoplasm grade III astrocytic tumour anaplastic astrocytoma malignant astrocytoma astrocytoma, anaplastic, malignant |
|
| id |
EFO:0002499 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disorder |
|
| label |
anaplastic astrocytoma |
|
| notation |
EFO:0002499 |
|
| preferred label |
anaplastic astrocytoma |
|
| prefLabel |
anaplastic astrocytoma |
|
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0016680 |