loading...| Preferred Name |
dermatomyositis |
|
| Synonyms |
Polydermatomyositis Polymyositis with skin involvement Polymyositis-Dermatomyositides [X]Dermatopolymyositis, unspecified Dermatopolymyositis, unspecified Dermatomyositides Adult Type Dermatomyositides Dermatomyositis, Childhood Type Polymyositis-Dermatomyositis DM - Dermatomyositis Dermatomyositides, Adult Type Polymyositis Dermatomyositis Wagner-Unverricht syndrome Dermatopolymyositis Adult Type Dermatomyositis [X]Dermatopolymyositis, unspecified (disorder) Dermatopolymyositides Dermatomyositis (disorder) dermatopolymyositis Dermatomyositis, Adult Type Dermatopolymyositis, unspecified (disorder) DM polymyositis with skin involvement dermatomyositis Amyopathic dermatomyositis adult dermatomyositis |
|
| Definitions |
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6) A myositis and is_a dermatitis that results_in inflammation located_in muscle and located_in skin. The disease may result from either a viral infection or an autoimmune reaction. Dermatomyositis (DM) is a type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0000398 |
|
| closeMatch | ||
| database_cross_reference |
SNOMEDCT:396230008 UMLS:C0011633 MedDRA:10012503 MeSH:D003882 NCIt:C26744 DOID:10223 ICD10:M33 ICD9:710.3 NCIT:C26744 Orphanet:221 GARD:6263 NORD:1048 SCTID:396230008 MESH:D003882 MONDO:0016367 |
|
| definition |
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6) A myositis and is_a dermatitis that results_in inflammation located_in muscle and located_in skin. The disease may result from either a viral infection or an autoimmune reaction. Dermatomyositis (DM) is a type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness. |
|
| disease has location | ||
| exactMatch |
http://linkedlifedata.com/resource/umls/id/C0011633 http://purl.obolibrary.org/obo/DOID_10223 http://purl.obolibrary.org/obo/Orphanet_221 http://identifiers.org/snomedct/396230008 |
|
| gwas_trait |
true |
|
| has_exact_synonym |
Polydermatomyositis Polymyositis with skin involvement Polymyositis-Dermatomyositides [X]Dermatopolymyositis, unspecified Dermatopolymyositis, unspecified Dermatomyositides Adult Type Dermatomyositides Dermatomyositis, Childhood Type Polymyositis-Dermatomyositis DM - Dermatomyositis Dermatomyositides, Adult Type Polymyositis Dermatomyositis Wagner-Unverricht syndrome Dermatopolymyositis Adult Type Dermatomyositis [X]Dermatopolymyositis, unspecified (disorder) Dermatopolymyositides Dermatomyositis (disorder) dermatopolymyositis Dermatomyositis, Adult Type Dermatopolymyositis, unspecified (disorder) DM polymyositis with skin involvement dermatomyositis |
|
| has_narrow_synonym |
adult dermatomyositis |
|
| has_related_synonym |
Amyopathic dermatomyositis |
|
| id |
EFO:0000398 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#nord_rare http://purl.obolibrary.org/obo/mondo#orphanet_rare |
|
| label |
dermatomyositis |
|
| notation |
EFO:0000398 |
|
| prefLabel |
dermatomyositis |
|
| term editor |
James Malone Gautier Koscielny |
|
| excluded_subClassOf |
http://purl.obolibrary.org/obo/MONDO_0019724 |
|
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0002406 http://www.ebi.ac.uk/efo/EFO_0003063 |