loading...| Preferred Name | dermatomyositis | |
| Synonyms |
adult dermatomyositis Amyopathic dermatomyositis dermatomyositis Polydermatomyositis Polymyositis with skin involvement Polymyositis-Dermatomyositides [X]Dermatopolymyositis, unspecified Dermatopolymyositis, unspecified Dermatomyositides Adult Type Dermatomyositides Dermatomyositis, Childhood Type Polymyositis-Dermatomyositis DM - Dermatomyositis Dermatomyositides, Adult Type Polymyositis Dermatomyositis Wagner-Unverricht syndrome Dermatopolymyositis Adult Type Dermatomyositis [X]Dermatopolymyositis, unspecified (disorder) Dermatopolymyositides Dermatomyositis (disorder) dermatopolymyositis Dermatomyositis, Adult Type Dermatopolymyositis, unspecified (disorder) polymyositis with skin involvement DM |
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| Definitions |
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6) Dermatomyositis (DM) is a type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness. A myositis and is_a dermatitis that results_in inflammation located_in muscle and located_in skin. The disease may result from either a viral infection or an autoimmune reaction. |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0000398 |
|
| closeMatch | ||
| database_cross_reference |
MEDGEN:8331 icd11.foundation:739030149 NANDO:1200274 SCTID:396230008 SNOMEDCT:396230008 UMLS:C0011633 Orphanet:221 NCIT:C26744 MESH:D003882 MONDO:0016367 MedDRA:10012503 MeSH:D003882 NCIt:C26744 DOID:10223 GARD:6263 ICD10:M33 ICD9:710.3 NORD:1048 |
|
| definition |
A subacute or chronic inflammatory disease of muscle and skin, marked by proximal muscle weakness and a characteristic skin rash. The illness occurs with approximately equal frequency in children and adults. The skin lesions usually take the form of a purplish rash (or less often an exfoliative dermatitis) involving the nose, cheeks, forehead, upper trunk, and arms. The disease is associated with a complement mediated intramuscular microangiopathy, leading to loss of capillaries, muscle ischemia, muscle-fiber necrosis, and perifascicular atrophy. The childhood form of this disease tends to evolve into a systemic vasculitis. Dermatomyositis may occur in association with malignant neoplasms. (From Adams et al., Principles of Neurology, 6th ed, pp1405-6) Dermatomyositis (DM) is a type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness. A myositis and is_a dermatitis that results_in inflammation located_in muscle and located_in skin. The disease may result from either a viral infection or an autoimmune reaction. |
|
| disease has location | ||
| exactMatch |
http://linkedlifedata.com/resource/umls/id/C0011633 http://purl.obolibrary.org/obo/DOID_10223 http://purl.obolibrary.org/obo/Orphanet_221 http://identifiers.org/snomedct/396230008 http://purl.obolibrary.org/obo/EFO_0000398 http://identifiers.org/mesh/D003882 http://purl.obolibrary.org/obo/NCIT_C26744 http://identifiers.org/medgen/8331 http://purl.obolibrary.org/obo/mondo/sources/icd11foundation/739030149 |
|
| gwas_trait |
true |
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| has_exact_synonym |
dermatomyositis Polydermatomyositis Polymyositis with skin involvement Polymyositis-Dermatomyositides [X]Dermatopolymyositis, unspecified Dermatopolymyositis, unspecified Dermatomyositides Adult Type Dermatomyositides Dermatomyositis, Childhood Type Polymyositis-Dermatomyositis DM - Dermatomyositis Dermatomyositides, Adult Type Polymyositis Dermatomyositis Wagner-Unverricht syndrome Dermatopolymyositis Adult Type Dermatomyositis [X]Dermatopolymyositis, unspecified (disorder) Dermatopolymyositides Dermatomyositis (disorder) dermatopolymyositis Dermatomyositis, Adult Type Dermatopolymyositis, unspecified (disorder) polymyositis with skin involvement DM |
|
| has_narrow_synonym |
adult dermatomyositis |
|
| has_related_synonym |
Amyopathic dermatomyositis |
|
| id |
EFO:0000398 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo/mondo-base#rare http://purl.obolibrary.org/obo/mondo/mondo-base#otar http://purl.obolibrary.org/obo/mondo/mondo-base#gard_rare http://purl.obolibrary.org/obo/mondo/mondo-base#orphanet_rare http://purl.obolibrary.org/obo/mondo/mondo-base#nord_rare http://purl.obolibrary.org/obo/mondo/mondo-base#ordo_disorder |
|
| label |
dermatomyositis |
|
| notation |
EFO:0000398 |
|
| preferred label |
dermatomyositis |
|
| prefLabel |
dermatomyositis |
|
| term editor |
James Malone Gautier Koscielny |
|
| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0002406 http://www.ebi.ac.uk/efo/EFO_0003063 |
|
| excluded_subClassOf |
http://purl.obolibrary.org/obo/MONDO_0019724 |