loading...| Preferred Name | acute monocytic leukemia | |
| Synonyms |
acute myeloblastic leukemia type 5 acute monoblastic leukemia acute monoblastic leukaemia leukemia, acute monocytic acute monoblastic/monocytic leukemia acute monoblastic/monocytic leukaemia acute myeloblastic leukaemia type 5 AML-M5 monocytic leukaemia monocytic leukemia acute monocytic leukemia, morphology (morphologic abnormality) acute monocytic leukaemia (FAB M5B) acute monocytic leukemia, FAB M5 acute monocytic leukemia (FAB M5B) acute monoblastic leukemia and acute monocytic leukemia acute monocytic leukemia without mention of remission acute monocytic leukemia (FAB M5b) acute monocytic leukemia, morphology monocytic leukemia, acute acute monocytic leukaemia (FAB M5b) acute monocytic leukemia acute monoblastic leukaemia and acute monocytic leukaemia acute monocytic leukaemia without mention of remission leukemia, monocytic, malignant AML M5 |
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| Definitions |
Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with asthenia, pallor, fever, and dizziness. Specific features of AML-M5 include hyperleukocytosis, propensity for extramedullary infiltrates, coagulation abnormalities including disseminated intravascular coagulation and neurological disorders. Leukemia cutis and gingival infiltration can also be seen. A characteristic translocation observed in AML-M5 is t(9;11). |
|
| ID |
http://www.ebi.ac.uk/efo/EFO_0000221 |
|
| closeMatch |
http://identifiers.org/snomedct/91859000 http://identifiers.org/snomedct/154594005 http://identifiers.org/snomedct/22331004 |
|
| conformsTo | ||
| database_cross_reference |
MEDGEN:7319 GARD:0000525 OMIM:151380 MESH:D007948 MedDRA:10059439 Orphanet:514 UMLS:C1318544 SCTID:413441006 UMLS:C0023465 EFO:0000221 NANDO:2200009 NANDO:2200008 COHD:135768 ONCOTREE:AMOL ICD10:C92.7 ICDO:9891/3 MONDO:0007896 CSP:2004-2820 MedDRA:10000871 icd11.foundation:517546180 DOID:8864 GARD:525 ICD9:206.0 NCIT:C4861 |
|
| definition |
Acute monoblastic leukemia (AML-M5), is one of the most common subtypes of acute myeloid leukemia (AML) that is either comprised of more than 80% of monoblasts (AML-M5a) or 30-80% monoblasts with (pro)monocytic differentiation (AML-M5b). AML-M5 presents with asthenia, pallor, fever, and dizziness. Specific features of AML-M5 include hyperleukocytosis, propensity for extramedullary infiltrates, coagulation abnormalities including disseminated intravascular coagulation and neurological disorders. Leukemia cutis and gingival infiltration can also be seen. A characteristic translocation observed in AML-M5 is t(9;11). |
|
| exactMatch |
http://identifiers.org/medgen/7319 http://identifiers.org/omim/151380 http://linkedlifedata.com/resource/umls/id/C0023465 http://linkedlifedata.com/resource/umls/id/C0457334 http://linkedlifedata.com/resource/umls/id/C1318544 http://purl.obolibrary.org/obo/NCIT_C4861 http://identifiers.org/mesh/D007948 http://identifiers.org/snomedct/413441006 http://identifiers.org/meddra/10000871 http://identifiers.org/meddra/10059439 |
|
| excluded_from_qc_check |
http://purl.obolibrary.org/obo/mondo/sparql/qc/mondo/qc-omim-subsumption.sparql |
|
| has_broad_synonym |
monocytic leukaemia monocytic leukemia |
|
| has_exact_synonym |
acute monocytic leukemia, morphology (morphologic abnormality) acute monocytic leukaemia (FAB M5B) acute monocytic leukemia, FAB M5 acute monocytic leukemia (FAB M5B) acute monoblastic leukemia and acute monocytic leukemia acute monocytic leukemia without mention of remission acute monocytic leukemia (FAB M5b) acute monocytic leukemia, morphology monocytic leukemia, acute acute monocytic leukaemia (FAB M5b) acute monocytic leukemia acute monoblastic leukaemia and acute monocytic leukaemia acute monocytic leukaemia without mention of remission leukemia, monocytic, malignant monocytic leukemia AML M5 |
|
| has_related_synonym |
acute myeloblastic leukemia type 5 acute monoblastic leukemia acute monoblastic leukaemia leukemia, acute monocytic acute monoblastic/monocytic leukemia acute monoblastic/monocytic leukaemia acute myeloblastic leukaemia type 5 AML-M5 |
|
| id |
EFO:0000221 |
|
| in_subset |
http://purl.obolibrary.org/obo/mondo#ordo_disorder http://purl.obolibrary.org/obo/mondo#ordo_disease http://purl.obolibrary.org/obo/mondo#rare http://purl.obolibrary.org/obo/mondo#nord_rare http://purl.obolibrary.org/obo/mondo#orphanet_rare |
|
| label |
acute monocytic leukemia |
|
| notation |
EFO:0000221 |
|
| preferred label |
acute monocytic leukemia |
|
| prefLabel |
acute monocytic leukemia |
|
| see also |
https://rarediseases.info.nih.gov/diseases/525/acute-monoblastic-leukemia |
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| excluded_subClassOf | ||
| subClassOf |