Preferred Name |
keratinocyte |
|
Synonyms |
malpighian cell keratinized cell of epidermis |
|
Definitions |
Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
|
ID |
http://purl.obolibrary.org/obo/CL_0000312 |
|
comment |
Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. |
|
database_cross_reference |
SNOMEDCT:74447004 CALOHA:TS-0500 ZFA:0009158 BTO:0000667 NCIt:C12589 FMA:62879 |
|
definition |
An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. |
|
has_exact_synonym |
malpighian cell keratinized cell of epidermis |
|
in_subset |
http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas |
|
label |
keratinocyte |
|
located_in | ||
prefixIRI |
CL:0000312 |
|
prefLabel |
keratinocyte |
|
RO_0002175 | ||
subClassOf |