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Experimental Factor Ontology
Last uploaded:
December 16, 2024
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| Preferred Name | verapamil | |
| Synonyms |
verapamilum verapamil verapamilo rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Verapamil |
|
| Definitions |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_9948 |
|
| charge |
0
|
|
| database_cross_reference |
HMDB:HMDB0001850 PMID:19125880 ChemIDplus:52-53-9 "CAS Registry Number" PMID:26046259 KEGG COMPOUND:C07188 "KEGG COMPOUND" PMID:12454681 DrugBank:DB00661 PMID:25331694 PMID:18093581 PMID:16545584 PMID:26553277 PMID:11975770 Beilstein:2825000 "Beilstein Registry Number" PMID:25650380 CAS:52-53-9 PMID:26567612 DrugBank:DB00661 "DrugBank" KEGG DRUG:D02356 "KEGG DRUG" PMID:14681337 SNOMEDCT:47898004 MeSH:D014700 PMID:25968157 PMID:11389609 SNOMEDCT:372754009 PMID:26504804 KEGG:C07188 PMID:17724247 PMID:24532601 PMID:8861548 PMID:24577794 PMID:11142488 KEGG:D02356 PMID:17525564 KEGG COMPOUND:52-53-9 "CAS Registry Number" PMID:11454724 Wikipedia:Verapamil Reaxys:2825000 PMID:18337499 PMID:25297337 NCIt:C928
|
|
| definition |
A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
|
|
| formula |
C27H38N2O4
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|
| has characteristic | ||
| has_exact_synonym |
rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile Verapamil
|
|
| has_obo_namespace |
chebi_ontology
|
|
| has_related_synonym |
verapamilum verapamil verapamilo
|
|
| has_role | ||
| id |
CHEBI:9948
|
|
| in_subset | ||
| label |
verapamil
|
|
| mass |
454.60160
|
|
| monoisotopicmass |
454.28316
|
|
| notation |
CHEBI:9948
|
|
| preferred label |
verapamil
|
|
| prefLabel |
verapamil
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|
| subClassOf |
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