loading...| Preferred Name | tramadol | |
| Synonyms |
(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol CG-315E E-265 U-26225A tramadol tramadolum rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol |
|
| Definitions |
A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_9648 |
|
| bearer of |
http://purl.obolibrary.org/obo/CHEBI_64054 http://purl.obolibrary.org/obo/CHEBI_50949 http://purl.obolibrary.org/obo/CHEBI_48878 http://purl.obolibrary.org/obo/CHEBI_48876 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_55322 http://purl.obolibrary.org/obo/CHEBI_48279 http://purl.obolibrary.org/obo/CHEBI_70774 http://purl.obolibrary.org/obo/CHEBI_35640 http://purl.obolibrary.org/obo/CHEBI_59282 http://purl.obolibrary.org/obo/CHEBI_78298 http://purl.obolibrary.org/obo/CHEBI_60643 |
|
| charge |
0 |
|
| formula |
C16H25NO2 |
|
| has exact synonym |
rac-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol |
|
| has part | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_64054 http://purl.obolibrary.org/obo/CHEBI_50949 http://purl.obolibrary.org/obo/CHEBI_48878 http://purl.obolibrary.org/obo/CHEBI_48876 http://purl.obolibrary.org/obo/CHEBI_35703 http://purl.obolibrary.org/obo/CHEBI_55322 http://purl.obolibrary.org/obo/CHEBI_48279 http://purl.obolibrary.org/obo/CHEBI_70774 http://purl.obolibrary.org/obo/CHEBI_35640 http://purl.obolibrary.org/obo/CHEBI_59282 http://purl.obolibrary.org/obo/CHEBI_78298 http://purl.obolibrary.org/obo/CHEBI_60643 |
|
| hasOBONamespace |
chebi_ontology |
|
| hasRelatedSynonym |
(+-)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol CG-315E E-265 U-26225A tramadol tramadolum |
|
| id |
CHEBI:9648 |
|
| inSubset | ||
| is conjugate base of | ||
| label |
tramadol |
|
| mass |
263.37520 |
|
| monoisotopicmass |
263.18853 |
|
| notation |
CHEBI:9648 |
|
| overlaps | ||
| prefLabel |
tramadol |
|
| textual definition |
A racemate consisting of equal amounts of (R,R)- and (S,S)-tramadol. A centrally acting synthetic opioid analgesic, used (as the hydrochloride salt) to treat moderately severe pain. The (R,R)-enantiomer exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. Originally developed by Gruenenthal GmbH and launched in 1977, it was subsequently isolated from the root bark of the South African tree Nauclea latifolia. |
|
| xRef |
PMID:23843224 PMID:23098678 PMID:23095734 PMID:23099620 PMID:23061925 PMID:23543914 HMDB:HMDB0014339 Reaxys:2943832 PMID:23292128 PMID:23031839 PMID:23962470 PMID:23872384 KEGG:D08623 PMID:23822079 PMID:25219922 PMID:23145962 Patent:US3652589 PMID:24014188 Wikipedia:Tramadol PMID:23756535 PMID:22964800 Patent:GB997399 PMID:23773348 PMID:23668411 PMID:22943675 PMID:23907474 KEGG:C07153 PMID:23433451 DrugBank:DB00193 PMID:23755929 PMID:23840975 CAS:27203-92-5 PMID:23825758 PMID:22674657 PMID:23328338 PMID:23102445 |
|
| subClassOf |