Drug Target Ontology

Last uploaded: February 15, 2018
Preferred Name

pancreatic islet
Synonyms
Definitions

Irregular microscopic structures scattered throughout the pancreas and comprising its endocrine part (the endocrine pancreas). In humans, they are composed of at least four types of cells: the alpha cells, which secrete glucagon; the beta cells, which are the most abundant and secrete insulin; the delta cells, which secrete somatostatin; and the PP cells, which secrete pancreatic polypeptide. Degeneration of the beta cells, whose secretion (insulin) is important in carbohydrate metabolism, is the major cause of type I diabetes mellitus.

ID

http://purl.obolibrary.org/obo/BTO_0000991

definition

Irregular microscopic structures scattered throughout the pancreas and comprising its endocrine part (the endocrine pancreas). In humans, they are composed of at least four types of cells: the alpha cells, which secrete glucagon; the beta cells, which are the most abundant and secrete insulin; the delta cells, which secrete somatostatin; and the PP cells, which secrete pancreatic polypeptide. Degeneration of the beta cells, whose secretion (insulin) is important in carbohydrate metabolism, is the major cause of type I diabetes mellitus.

hasOBONamespace

BrendaTissueOBO

hasRelatedSynonym

island of pancreas

islet of Langerhans

island of Langerhans

id

BTO:0000991

imported from

http://purl.obolibrary.org/obo/bto.owl

label

pancreatic islet

prefixIRI

BTO:0000991

prefLabel

pancreatic islet

subClassOf

http://www.drugtargetontology.org/dto/DTO_00000018

Delete Subject Author Type Created
No notes to display