loading...| Preferred Name |
myelodysplastic syndrome |
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| Synonyms |
myelodysplasia myelodysplastic syndromes MDS smoldering leukemia myelodysplastic syndrome/neoplasm preleukemia myelodysplastic syndrome oligoblastic leukemia myelodysplastic syndrome, unclassifiable myelodysplastic neoplasm MDS-U MDS, unclassifiable myelodysplastic syndrome, somatic dysmyelopoietic syndrome hematopoeitic - myelodysplastic syndrome (MDS) myelodysplastic syndrome, susceptibility to |
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| Definitions |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0018881 |
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| disease has feature | ||
| has_exact_synonym |
myelodysplasia myelodysplastic syndromes MDS smoldering leukemia myelodysplastic syndrome/neoplasm preleukemia myelodysplastic syndrome oligoblastic leukemia myelodysplastic syndrome, unclassifiable myelodysplastic neoplasm MDS-U MDS, unclassifiable myelodysplastic syndrome, somatic dysmyelopoietic syndrome hematopoeitic - myelodysplastic syndrome (MDS) |
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| has_related_synonym |
myelodysplastic syndrome, susceptibility to |
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| IAO_0000233 | ||
| label |
myelodysplastic syndrome |
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| prefixIRI |
MONDO:0018881 |
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| prefLabel |
myelodysplastic syndrome |
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| textual definition |
A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001) |
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| subClassOf |