loading...| Preferred Name | agammaglobulinemia | |
| Synonyms |
Gammaglobulin Deficiency antibody Deficiency Immunoglobulin Deficiency hypogammaglobulinemia agammaglobulinemia IGHM mu heavy chain deficiency |
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| Definitions |
A decreased level of serum immunoglobulins. It may be inherited or acquired. It is caused by decreased or inefficient production of immunoglobulins from B cells or by a decrease in the numbers of B cells themselves. Low levels of immunoglobulins will affect the immune system's ability to combat bacterial infection. Supplementation of immunoglobulins is needed to prevent worsening outcomes. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0015977 |
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| altLabel |
Gammaglobulin Deficiency antibody Deficiency Immunoglobulin Deficiency hypogammaglobulinemia agammaglobulinemia IGHM mu heavy chain deficiency |
|
| definition |
A decreased level of serum immunoglobulins. It may be inherited or acquired. It is caused by decreased or inefficient production of immunoglobulins from B cells or by a decrease in the numbers of B cells themselves. Low levels of immunoglobulins will affect the immune system's ability to combat bacterial infection. Supplementation of immunoglobulins is needed to prevent worsening outcomes. |
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| has_exact_synonym |
hypogammaglobulinemia agammaglobulinemia IGHM mu heavy chain deficiency |
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| has_related_synonym |
Gammaglobulin Deficiency antibody Deficiency Immunoglobulin Deficiency |
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| label |
agammaglobulinemia |
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| prefixIRI |
MONDO:0015977 |
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| prefLabel |
agammaglobulinemia |
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| textual definition |
A decreased level of serum immunoglobulins. It may be inherited or acquired. It is caused by decreased or inefficient production of immunoglobulins from B cells or by a decrease in the numbers of B cells themselves. Low levels of immunoglobulins will affect the immune system's ability to combat bacterial infection. Supplementation of immunoglobulins is needed to prevent worsening outcomes. |
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| subClassOf |