loading...| Preferred Name |
scurvy |
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| Synonyms |
vitamin C deficiency deficiency of vitamin C scurvy ascorbic acid deficiency L-gulonolactone oxidase, nonfunctional scorbutus L-gulonolactone oxidase pseudogene vitamin C, inability to synthesize Gulo, nonfunctional hypoascorbemia |
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| Definitions |
An argument can be made that Vitamin C deficiency is a genetic disease shared by all humans, due to our loss of the GULO gene. See OMIM for discussion. Here we choose not to treat as genetic. A condition that develops in people who do not consume an adequate amount of vitamin C in their diet. Although scurvy is relatively rare in the United States, it continues to be a problem in malnourished populations around the world (such as impoverished, underdeveloped third world countries). Early features of the condition include general weakness, fatigue and aching limbs. If left untreated, more serious problems can develop such as anemia, gum disease, and skin hemorrhages. Symptoms generally develop after at least 3 months of severe or total vitamin C deficiency. Scurvy can be cured with vitamin C supplements taken by mouth. Once recovery is complete, dietary modifications to ensure the 'recommended daily intake' of vitamin C is reached will prevent relapse. Except in the case of severe dental disease, permanent damage from scurvy does not usually occur. |
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| ID |
http://purl.obolibrary.org/obo/MONDO_0009412 |
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| comment |
An argument can be made that Vitamin C deficiency is a genetic disease shared by all humans, due to our loss of the GULO gene. See OMIM for discussion. Here we choose not to treat as genetic. |
|
| has_exact_synonym |
vitamin C deficiency deficiency of vitamin C scurvy ascorbic acid deficiency |
|
| has_related_synonym |
L-gulonolactone oxidase, nonfunctional scorbutus L-gulonolactone oxidase pseudogene vitamin C, inability to synthesize Gulo, nonfunctional hypoascorbemia |
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| IAO_0000233 | ||
| label |
scurvy |
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| prefixIRI |
MONDO:0009412 |
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| prefLabel |
scurvy |
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| seeAlso | ||
| textual definition |
A condition that develops in people who do not consume an adequate amount of vitamin C in their diet. Although scurvy is relatively rare in the United States, it continues to be a problem in malnourished populations around the world (such as impoverished, underdeveloped third world countries). Early features of the condition include general weakness, fatigue and aching limbs. If left untreated, more serious problems can develop such as anemia, gum disease, and skin hemorrhages. Symptoms generally develop after at least 3 months of severe or total vitamin C deficiency. Scurvy can be cured with vitamin C supplements taken by mouth. Once recovery is complete, dietary modifications to ensure the 'recommended daily intake' of vitamin C is reached will prevent relapse. Except in the case of severe dental disease, permanent damage from scurvy does not usually occur. |
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| subClassOf |
http://purl.obolibrary.org/obo/MONDO_0045022 |