Preferred Name

mixed connective tissue disease

Synonyms

connective tissue disease overlap syndrome

MCTD

sharp syndrome

mixed collagen vascular disease

Definitions

Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that is characterized by features commonly seen in three different connective tissue disorders: systemic lupus erythematosus, scleroderma, and polymyositis. Some affected people may also have symptoms of rheumatoid arthritis. Although MCTD can affect people of all ages, it appears to be most common in women under age 30. Signs and symptoms vary but may include Raynaud's phenomenon ; arthritis; heart, lung and skin abnormalities; kidney disease; muscle weakness, and dysfunction of the esophagus. The cause of MCTD is currently unknown. There is no cure but certain medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids and immunosuppresivedrugsmay help manage the symptoms.

ID

http://purl.obolibrary.org/obo/MONDO_0005854

altLabel

connective tissue disease overlap syndrome

MCTD

sharp syndrome

mixed collagen vascular disease

definition

Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that is characterized by features commonly seen in three different connective tissue disorders: systemic lupus erythematosus, scleroderma, and polymyositis. Some affected people may also have symptoms of rheumatoid arthritis. Although MCTD can affect people of all ages, it appears to be most common in women under age 30. Signs and symptoms vary but may include Raynaud's phenomenon ; arthritis; heart, lung and skin abnormalities; kidney disease; muscle weakness, and dysfunction of the esophagus. The cause of MCTD is currently unknown. There is no cure but certain medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids and immunosuppresivedrugsmay help manage the symptoms.

has_exact_synonym

connective tissue disease overlap syndrome

MCTD

sharp syndrome

mixed collagen vascular disease

label

mixed connective tissue disease

prefixIRI

MONDO:0005854

prefLabel

mixed connective tissue disease

seeAlso

https://rarediseases.info.nih.gov/diseases/7051/mixed-connective-tissue-disease

textual definition

Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that is characterized by features commonly seen in three different connective tissue disorders: systemic lupus erythematosus, scleroderma, and polymyositis. Some affected people may also have symptoms of rheumatoid arthritis. Although MCTD can affect people of all ages, it appears to be most common in women under age 30. Signs and symptoms vary but may include Raynaud's phenomenon ; arthritis; heart, lung and skin abnormalities; kidney disease; muscle weakness, and dysfunction of the esophagus. The cause of MCTD is currently unknown. There is no cure but certain medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids and immunosuppresivedrugsmay help manage the symptoms.

subClassOf

http://purl.obolibrary.org/obo/MONDO_0005554

http://purl.obolibrary.org/obo/MONDO_0016663

http://purl.obolibrary.org/obo/MONDO_0019724

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