Preferred Name | B-cell chronic lymphocytic leukemia | |
Synonyms |
small lymphocytic lymphoma leukemia, chronic LYMPHOCYTIC leukemia, lymphocytic, chronic leukemia, chronic lymphatic B-cell CLL B cell chronic lymphocytic leukemia B-cell chronic lymphoid leukemia B cell lymphocytic leukemia B-cell chronic lymphocytic leukemia lymphoplasmacytic leukemia BCLL hematopoeitic - chronic lymphocytic leukemia (CLL) B cell CLL chronic B-cell lymphocytic leukemia CLL chronic lymphocytic leukemia chronic lymphocytic leukemia (CLL) chronic lymphatic leukemia B-cell chronic lymphogenous leukemia B-CLL chronic lymphogenous leukemia B-cell lymphocytic leukemia |
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Definitions |
B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma, and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia. The clinical course is extremely heterogeneous with survival ranging from a few months to several decades. |
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ID |
http://purl.obolibrary.org/obo/MONDO_0004948 |
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altLabel |
small lymphocytic lymphoma leukemia, chronic LYMPHOCYTIC leukemia, lymphocytic, chronic leukemia, chronic lymphatic B-cell CLL B cell chronic lymphocytic leukemia B-cell chronic lymphoid leukemia B cell lymphocytic leukemia B-cell chronic lymphocytic leukemia lymphoplasmacytic leukemia BCLL hematopoeitic - chronic lymphocytic leukemia (CLL) B cell CLL chronic B-cell lymphocytic leukemia CLL chronic lymphocytic leukemia chronic lymphocytic leukemia (CLL) chronic lymphatic leukemia B-cell chronic lymphogenous leukemia B-CLL chronic lymphogenous leukemia B-cell lymphocytic leukemia |
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definition |
B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma, and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia. The clinical course is extremely heterogeneous with survival ranging from a few months to several decades. |
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has_exact_synonym |
B-cell CLL B cell chronic lymphocytic leukemia B-cell chronic lymphoid leukemia B cell lymphocytic leukemia B-cell chronic lymphocytic leukemia lymphoplasmacytic leukemia BCLL hematopoeitic - chronic lymphocytic leukemia (CLL) B cell CLL chronic B-cell lymphocytic leukemia CLL chronic lymphocytic leukemia chronic lymphocytic leukemia (CLL) chronic lymphatic leukemia B-cell chronic lymphogenous leukemia B-CLL chronic lymphogenous leukemia B-cell lymphocytic leukemia |
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has_related_synonym |
small lymphocytic lymphoma leukemia, chronic LYMPHOCYTIC leukemia, lymphocytic, chronic leukemia, chronic lymphatic |
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label |
B-cell chronic lymphocytic leukemia |
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prefixIRI |
MONDO:0004948 |
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prefLabel |
B-cell chronic lymphocytic leukemia |
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textual definition |
B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma, and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia. The clinical course is extremely heterogeneous with survival ranging from a few months to several decades. |
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subClassOf |
http://purl.obolibrary.org/obo/MONDO_0004949 http://purl.obolibrary.org/obo/MONDO_0004967 |