The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	methamphetamine
Synonyms	methyl[(2S)-1-phenylpropan-2-yl]amine C10H15N
ID	http://purl.obolibrary.org/obo/dinto_DB01577
activates	http://purl.obolibrary.org/obo/dinto_1314 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_1135
ATCCode	N06BA03
binds	http://purl.obolibrary.org/obo/dinto_1673 http://purl.obolibrary.org/obo/dinto_1972 http://purl.obolibrary.org/obo/dinto_3613 http://purl.obolibrary.org/obo/dinto_2834 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_2789 http://purl.obolibrary.org/obo/dinto_3622 http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_3343 http://purl.obolibrary.org/obo/dinto_0068 http://purl.obolibrary.org/obo/dinto_1314 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_1135
CASRN	537-46-2
DBBrand	desyphed hydrochloride desoxyn metamfetamine stimulex metamfetamine-m norodin desyphed speed
DBSynonym	(s)-methylamphetamine d-1-phenyl-2-methylaminopropan [german] meth d-n,alpha-dimethylphenethylamine (+)-n-methylamphetamine d-1-phenyl-2-methylaminopropane d-phenylisopropylmethylamine d-n-methylamphetamine (+)-n,alpha-dimethyl-beta-phenylethylamine n-methyl-beta-phenylisopropylamin [german] (s)-n,alpha-dimethylbenzeneethanoamine (+)-(s)-n-alpha-dimethylphenethylamine (+)-(s)-deoxyephedrine (+)-methamphetamine d-desoxyephedrine ice methamphetaminum [inn-latin] d-methylamphetamine (s)-(+)-n,alpha,dimethylphenethylamine (+ )-methylamphetamine d-deoxyephedrine (s)-methamphetamine metamfetaminum [inn-latin] metamphetamine methyl-beta-phenylisopropylamine 2s-(+)-methamphetamine d-methamphetamine metamfetamina [inn-spanish] methylamphetamine (+)-2-(n-methylamino)-1-phenylpropane n-methyl-1-phenyl-2-propanamine desoxyephedrine hydrochloride (+)-n,alpha-dimethylphenethylamine (+)-methylamphetamine 1-phenyl-2-methylaminopropane metanfetamina [inn-spanish] l-methamphetamine (s)-(+)-deoxyephedrine n-methyl-beta-phenylisopropylamine (s)-(+)-methamphetamine (2s)-n-methyl-1-phenylpropan-2-amine s-(+)-methamphetamine (s)-n,alpha-dimethylbenzeneethanamine 1-phenyl-2-methylamino-propan [german] d-(s)-methamphetamine n-methylamphetamine
Definition	Methamphetamine is a psychostimulant and sympathomimetic drug. It is a member of the amphetamine group of sympathomimetic amines. Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. It is a scheduled drug in most countries due to its high potential for addiction and abuse.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000500
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1673 http://purl.obolibrary.org/obo/dinto_3613 http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_3343 http://purl.obolibrary.org/obo/dinto_1314 http://purl.obolibrary.org/obo/dinto_2834 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0068 http://purl.obolibrary.org/obo/dinto_1135 http://purl.obolibrary.org/obo/dinto_3622
InChI	InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1
InChIKey	InChIKey=MYWUZJCMWCOHBA-VIFPVBQESA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1673 http://purl.obolibrary.org/obo/dinto_1972 http://purl.obolibrary.org/obo/dinto_3613 http://purl.obolibrary.org/obo/dinto_2834 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_2789 http://purl.obolibrary.org/obo/dinto_3622
is metabolised by	http://purl.obolibrary.org/obo/dinto_2993
is substrate of	http://purl.obolibrary.org/obo/dinto_2993
label	methamphetamine
may interact with	http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/dinto_DB00519 http://purl.obolibrary.org/obo/CHEBI_31981 http://purl.obolibrary.org/obo/CHEBI_6838 http://purl.obolibrary.org/obo/CHEBI_8028 http://purl.obolibrary.org/obo/CHEBI_7936 http://purl.obolibrary.org/obo/CHEBI_3647 http://purl.obolibrary.org/obo/dinto_DB00857 http://purl.obolibrary.org/obo/CHEBI_45951 http://purl.obolibrary.org/obo/CHEBI_6780 http://purl.obolibrary.org/obo/CHEBI_9566 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_5123 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_5138 http://purl.obolibrary.org/obo/CHEBI_8461 http://purl.obolibrary.org/obo/CHEBI_8435 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_5557 http://purl.obolibrary.org/obo/CHEBI_63620 http://purl.obolibrary.org/obo/CHEBI_5118
modulates	http://purl.obolibrary.org/obo/dinto_1314 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_1135
prefixIRI	obo2:dinto_DB01577
prefLabel	methamphetamine
related with	http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_3343 http://purl.obolibrary.org/obo/dinto_0068
SMILES	CN[C@@H](C)CC1=CC=CC=C1
Synonym	methyl[(2S)-1-phenylpropan-2-yl]amine C10H15N
xref	National Drug Code Directory:0378-8115-01 ChEBI:6809 ChemSpider:10379 Drugs.com:http://www.drugs.com/methamphetamine.html PharmGKB:PA450403 PubChem Compound:10836 PubChem Substance:46508541 Wikipedia:http://en.wikipedia.org/wiki/Methamphetamine RxList:http://www.rxlist.com/cgi/generic/methamphetamine.htm
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_6809	OBA	LOOM
http://purl.obolibrary.org/obo/XCO_0001316	XCO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008694	RH-MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/6816	RXNORM	LOOM
http://purl.bioontology.org/ontology/VANDF/4019821	VANDF	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8024	OCHV	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU005018	LOINC	LOOM
http://purl.bioontology.org/ontology/MESH/D008694	MESH	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0025611	HFO	LOOM
http://purl.obolibrary.org/obo/MESH_D008694	BERO	LOOM
http://purl.bioontology.org/ontology/LNC/LP16194-0	LOINC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147910	NDFRT	LOOM
http://purl.obolibrary.org/obo/NCIT_C61840	BERO	LOOM
http://purl.jp/bio/4/id/200906071236937861	IOBC	LOOM
http://www.projecthalo.com/aura#Methamphetamine	AURA	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.471.683.152.619	RH-MESH	LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Methamphetamine	APAONTO	LOOM
http://stirdf.jst.go.jp/id/200907011725420643	IOBC	LOOM
http://purl.bioontology.org/ontology/LNC/LA15259-7	LOINC	LOOM
http://purl.bioontology.org/ontology/LNC/LP32102-3	LOINC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61840	NCIT	LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0025611	MEDLINEPLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	CCONT	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	GO-PLUS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	GSSO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_6809	ECTO	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387499002	SNOMEDCT	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016156	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/CSP/2268-6486	CRISP	LOOM
http://purl.bioontology.org/ontology/SNMI/C-65050	SNMI	LOOM
http://doe-generated-ontology.com/OntoAD#C0025611	ONTOAD	LOOM
http://www.drugbank.ca/drugs/DB01577	FTC	LOOM
http://purl.obolibrary.org/obo/OMIT_0009757	OMIT	LOOM