The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

levamisole
Synonyms

C11H12N2S

(6S)-6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole
ID

http://purl.obolibrary.org/obo/dinto_DB00848
activates

http://purl.obolibrary.org/obo/dinto_0150
ATCCode

P02CE01
binds

http://purl.obolibrary.org/obo/dinto_4071

http://purl.obolibrary.org/obo/dinto_0150
CASRN

14769-73-4
DBBrand

wormicid

nilverm base

lepuron

tetramisole

ketrax

tramisol

tetramisol

vermisol 150

ergamisol
DBSynonym

phenyl imidothiazole

levamisolum [inn-latin]

levamisole hydrochloride

dl-tetramisole

l-tetramisole

levamisol [inn-spanish]

dl-tetramisol
Definition

An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6)
has pharmacological target

http://purl.obolibrary.org/obo/dinto_0150
InChI

InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1
InChIKey

InChIKey=HLFSDGLLUJUHTE-SNVBAGLBSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_4071
label

levamisole
may interact with

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/CHEBI_4513
modulates

http://purl.obolibrary.org/obo/dinto_0150
prefixIRI

obo2:dinto_DB00848
prefLabel

levamisole
SMILES

C1CN2C[C@@H](N=C2S1)C1=CC=CC=C1
Synonym

C11H12N2S

(6S)-6-phenyl-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole
xref

ChemSpider:25037

Drugs Product Database (DPD):645699

PubChem Substance:46509052

Wikipedia:http://en.wikipedia.org/wiki/Levamisole

RxList:http://www.rxlist.com/cgi/generic3/levamisole.htm

PharmGKB:PA450205

BindingDB:50241179

Drugs.com:http://www.drugs.com/mtm/levamisole.html

PubChem Compound:26879
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.708.346 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU035824 LOINC LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61609 NCIT LOOM
http://www.drugbank.ca/drugs/DB00848 FTC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387296006 SNOMEDCT LOOM
http://purl.obolibrary.org/obo/OMIT_0009063 OMIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0023556 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4019531 VANDF LOOM
http://purl.bioontology.org/ontology/NDDF/004809 NDDF LOOM
https://go.drugbank.com/drugs/DB00848 MDM LOOM
http://purl.bioontology.org/ontology/MESH/D007978 MESH LOOM
http://purl.obolibrary.org/obo/MESH_D007978 BERO LOOM
http://purl.bioontology.org/ontology/SNMI/C-56A96 SNMI LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147645 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7375 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.129.308.480 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017466 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D007978 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 UPHENO LOOM
http://purl.obolibrary.org/obo/CHEBI_6432 ECTO LOOM
http://purl.bioontology.org/ontology/ATC/P02CE01 ATC LOOM
http://purl.bioontology.org/ontology/RCD/x02MJ RCD LOOM
http://purl.bioontology.org/ontology/RXNORM/6371 RXNORM LOOM
http://purl.bioontology.org/ontology/CSP/1549-4587 CRISP LOOM
http://purl.bioontology.org/ontology/LNC/LP100040-7 LOINC LOOM
http://purl.jp/bio/4/id/200906029458438930 IOBC LOOM
http://stirdf.jst.go.jp/id/200907018342038561 IOBC LOOM
http://www.co-ode.org/ontologies/galen#Levamisole GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.675.346 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C61609 BERO LOOM