The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

antithrombin-iii
Synonyms

antithrombin-iii precursor

atiii
ID

http://purl.obolibrary.org/obo/dinto_1192
binds

http://purl.obolibrary.org/obo/dinto_DB01225

http://purl.obolibrary.org/obo/dinto_DB06271

http://purl.obolibrary.org/obo/dinto_DB06779

http://purl.obolibrary.org/obo/dinto_DB00569

http://purl.obolibrary.org/obo/dinto_DB06822

http://purl.obolibrary.org/obo/dinto_DB04464

http://purl.obolibrary.org/obo/dinto_DB02944

http://purl.obolibrary.org/obo/dinto_DB00407

http://purl.obolibrary.org/obo/CHEBI_28304

http://purl.obolibrary.org/obo/dinto_DB08813
Definition

Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin
definition source

DrugBank Database
Gene

serpinc1
is binded by

http://purl.obolibrary.org/obo/dinto_DB01225

http://purl.obolibrary.org/obo/dinto_DB06271

http://purl.obolibrary.org/obo/dinto_DB06779

http://purl.obolibrary.org/obo/dinto_DB00569

http://purl.obolibrary.org/obo/dinto_DB06822

http://purl.obolibrary.org/obo/dinto_DB00407

http://purl.obolibrary.org/obo/CHEBI_28304

http://purl.obolibrary.org/obo/dinto_DB08813
is pharmacological target of

http://purl.obolibrary.org/obo/dinto_DB01225

http://purl.obolibrary.org/obo/dinto_DB06271

http://purl.obolibrary.org/obo/dinto_DB06779

http://purl.obolibrary.org/obo/dinto_DB00569

http://purl.obolibrary.org/obo/dinto_DB06822

http://purl.obolibrary.org/obo/dinto_DB00407

http://purl.obolibrary.org/obo/CHEBI_28304

http://purl.obolibrary.org/obo/dinto_DB08813
label

antithrombin-iii
OrganismClass

human
prefixIRI

obo2:dinto_1192
prefLabel

antithrombin-iii
related with

http://purl.obolibrary.org/obo/dinto_DB01225

http://purl.obolibrary.org/obo/dinto_DB06271

http://purl.obolibrary.org/obo/dinto_DB06779

http://purl.obolibrary.org/obo/dinto_DB00569

http://purl.obolibrary.org/obo/dinto_DB06822

http://purl.obolibrary.org/obo/dinto_DB04464

http://purl.obolibrary.org/obo/dinto_DB02944

http://purl.obolibrary.org/obo/dinto_DB00407

http://purl.obolibrary.org/obo/CHEBI_28304

http://purl.obolibrary.org/obo/dinto_DB08813
Synonym

antithrombin-iii precursor

atiii
xref

UniProt ID:P01008

DrugBank:309
subClassOf

http://purl.obolibrary.org/obo/dinto_000128
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Mapping To Ontology Source
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Antithrombin-III SEPON LOOM
http://purl.obolibrary.org/obo/NCIT_C104683 BERO LOOM
http://purl.obolibrary.org/obo/DRON_00012870 DRON LOOM
http://purl.obolibrary.org/obo/DRON_00012870 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00012870 DDSS LOOM
http://purl.jp/bio/4/id/200906075874884142 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.822.750.060.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/1009 RXNORM LOOM
http://purl.bioontology.org/ontology/ATC/B01AB02 ATC LOOM
http://purl.bioontology.org/ontology/RCD/X80WP RCD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00021438 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D23.113.025 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.377.715.085.125 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0003438 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4023295 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.861.060.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/PR_000003252 PR LOOM
http://purl.obolibrary.org/obo/PR_000003252 PDRO LOOM
http://purl.obolibrary.org/obo/PR_000003252 OBI LOOM
http://purl.obolibrary.org/obo/PR_000003252 ONE LOOM
http://purl.obolibrary.org/obo/PR_000003252 EGO LOOM
http://purl.obolibrary.org/obo/PR_000003252 OBI_IEE LOOM
http://purl.obolibrary.org/obo/PR_000003252 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.872.060.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#1327 OCHV LOOM
http://purl.bioontology.org/ontology/SNMI/F-D8320 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.124.790.106.125 RH-MESH LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:02389 MIO LOOM
http://purl.bioontology.org/ontology/CSP/0437-1452 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.776.645.750.060.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/MESH_D000990 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000021300 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000990 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C104683 NCIT LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/34086003 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MEDDRA/10050640 MEDDRA LOOM
http://purl.bioontology.org/ontology/MESH/D000990 MESH LOOM
http://purl.uniprot.org/uniprot/P01008 FTC LOOM
http://purl.obolibrary.org/obo/OMIT_0002384 OMIT LOOM